Copyright 2024
| PMID | Allele | Disease | Population | Drug Names | SNP | Class | Sentence |
|---|---|---|---|---|---|---|---|
| 23318129 | HLA-DQB1*03 | hernia | NA | NA | NA | unclassified | |
| in conclusion, we here for the first time demonstrate that there is an hla-dependent risk of developing pain after surgery or lumbar disc herniation; mediated by the drb1*04 - dqb1*03:02 haplotype. | |||||||
| 31486733 | HLA-B (HLA-B) | chronic pain | NA | NA | NA | unclassified | |
| genetic variations associated with drug effectiveness or adverse reactions (amitriptyline/nortriptyline/codeine/oxycodone/tramadol-cyp2d6, amitriptyline-cyp2c19, carbamazepine-hla-a, carbamazepine/oxcarbazepine-hla-b) can be used to guide chronic pain management. | |||||||
| 31486733 | HLA-A (HLA-A) | chronic pain | NA | NA | NA | unclassified | |
| genetic variations associated with drug effectiveness or adverse reactions (amitriptyline/nortriptyline/codeine/oxycodone/tramadol-cyp2d6, amitriptyline-cyp2c19, carbamazepine-hla-a, carbamazepine/oxcarbazepine-hla-b) can be used to guide chronic pain management. | |||||||
| 23354834 | HLA-DR (HLA-DR) | wallerian degeneration | NA | NA | NA | unclassified | |
| with immunohistochemical methods, the spatial relation of the two phenomena was visualized using hla-dr antibody for mhc ii expression by activated microglia/macrophages and by applying antibodies against damaged axons, i.e., smi32 (non-phosphorylated neurofilaments) and amyloid precursor protein as well as neuropeptide y receptor y1, which marks axons undergoing wallerian degeneration. | |||||||
| 23541412 | HLA-G (HLA-G) | african trypanosomiasis | African | NA | NA | unclassified | |
| hla-g 3' utr-2 haplotype is associated with human african trypanosomiasis susceptibility. | |||||||
| 23583993 | HLA-DRB1 (HLA-DRB1) | type 1 autoimmune pancreatitis | NA | NA | NA | unclassified | |
| type 1 autoimmune pancreatitis (aip) is characterized by a high serum igg4 concentration and is closely associated with the hla-drb1(*)04:05-dqb1(*)04:01 haplotype, for which family studies may disclose its immunogenetic significance. | |||||||
| 23583993 | HLA-DQB1 (HLA-DQB1) | type 1 autoimmune pancreatitis | NA | NA | NA | unclassified | |
| type 1 autoimmune pancreatitis (aip) is characterized by a high serum igg4 concentration and is closely associated with the hla-drb1(*)04:05-dqb1(*)04:01 haplotype, for which family studies may disclose its immunogenetic significance. | |||||||
| 23583993 | HLA-DRB1 (HLA-DRB1) | type 1 autoimmune pancreatitis | NA | NA | NA | positive+negation | |
| contrary to our expectations, the siblings showed only normal or slightly elevated values of serum igg4 and no hla drb1(*)04:05-dqb1(*)04:01 haplotype, suggesting that type 1 autoimmune pancreatitis is associated with multiple immunogenetic factors. | |||||||
| 23583993 | HLA-DQB1 (HLA-DQB1) | type 1 autoimmune pancreatitis | NA | NA | NA | positive+negation | |
| contrary to our expectations, the siblings showed only normal or slightly elevated values of serum igg4 and no hla drb1(*)04:05-dqb1(*)04:01 haplotype, suggesting that type 1 autoimmune pancreatitis is associated with multiple immunogenetic factors. | |||||||
| 23742355 | HLA (HLA) | clutter | NA | NA | NA | unclassified | |
| finally, the algorithm is experimentally demonstrated using data from a bottom-mounted hla deployed in the moderately cluttered continental shelf environment of the florida straits. | |||||||
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