Copyright 2024
| PMID | Allele | Disease | Population | Drug Names | SNP | Class | Sentence |
|---|---|---|---|---|---|---|---|
| 31765953 | HLA-G (HLA-G) | neuromyelitis optica spectrum disorder | Brazilian | NA | NA | unclassified | |
| we analyzed the association of polymorphisms from the 3' untranslated region of the hla-g gene in 70 neuromyelitis optica spectrum disorder (nmosd) patients and 162 healthy controls. | |||||||
| 34335680 | HLA-CLASS II (HLA CLASS II) | NA | Non European | rs17028450 | rs9272219 | unclassified | |
| NA | |||||||
| 23046723 | HLA-DR (HLA-DR) | prehypertension | NA | isoproterenol | NA | unclassified | |
| we compared nonclassical (cd14(+)cd16(++); hla-dr(+)), intermediate (cd14(++)cd16(+); hla-dr(++)), and classical (cd14(++)cd16(-); hla-dr(+/-)) monocyte trafficking and their lps-stimulated tnf production in response to a physical stressor (20-min treadmill exercise at 65-70% vo(2peak)) in participants with high prehypertension (pht), mild pht or normal bp (nbp). | |||||||
| 23046935 | HLA-DR (HLA-DR) | heart transplantations | NA | NA | NA | unclassified | |
| the expressions of pkc-theta, mhc-ii, serine/threonine kinase, tyrosine phosphatase, serine/threonine kinase 15, clotting factor viii, interferon gamma-inducible protein 16 and hla-dr-h increased by three times compared to pre-transplantation in patients with kidney and heart transplantations. | |||||||
| 23137327 | HLA-B*40 | chloroma | Chinese | NA | NA | only_studied | |
| identification of a new allele hla-b*40:213 by polymerase chain reaction sequence based typing in a chinese patient suffering from chloroma. | |||||||
| 23318129 | HLA-DQB1 (HLA-DQB1) | inguinal hernia | NA | NA | NA | positive | |
| the dqb1 *03:02 hla haplotype is associated with increased risk of chronic pain after inguinal hernia surgery and lumbar disc herniation. | |||||||
| 23318129 | HLA-DQB1 (HLA-DQB1) | chronic pain | NA | NA | NA | positive | |
| the dqb1 *03:02 hla haplotype is associated with increased risk of chronic pain after inguinal hernia surgery and lumbar disc herniation. | |||||||
| 23318129 | HUMAN LEUKOCYTE ANTIGEN (HUMAN LEUKOCYTE ANTIGEN) | inguinal hernia | NA | NA | NA | unclassified | |
| in order to study if the corresponding human leukocyte antigen complex (hla) also influences susceptibility to pain, we performed an association study in patients that had undergone surgery for inguinal hernia (n=189). | |||||||
| 23318129 | HLA-DQB1*03 | hernia | NA | NA | NA | unclassified | |
| this finding was subsequently replicated in the clinical material of patients with lumbar disc herniation (n=258), where carriers of the dqb1*03:02 allele displayed a slower recovery and increased pain. | |||||||
| 23318129 | HLA-DRB1*04 | hernia | NA | NA | NA | unclassified | |
| in conclusion, we here for the first time demonstrate that there is an hla-dependent risk of developing pain after surgery or lumbar disc herniation; mediated by the drb1*04 - dqb1*03:02 haplotype. | |||||||
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