Copyright 2024
| PMID | Allele | Disease | Population | Drug Names | SNP | Class | Sentence |
|---|---|---|---|---|---|---|---|
| 31145192 | HLA-B*57 | abacavir | NA | efavirenz | NA | unclassified | |
| NA | |||||||
| 22228344 | HLA (HLA) | tendonitis | NA | NA | NA | unclassified | |
| we are describing imaging characteristics in a patient with positive hla b-27 antigen with bilateral calcific achilles tendonitis who had pain in heels for 3 years. | |||||||
| 22231464 | HLA MISMATCHED (HLA-MISMATCHED) | transplantation haploidentical | NA | NA | NA | unclassified | |
| the role of hla antibodies in sct has drawn increasing attention because of the significantly increased number of patients who receive hla-mismatched sct, including cord blood transplantation, haploidentical sct and unrelated sct. | |||||||
| 22232945 | HLA-B*27 | musculoskeletal diseases | NA | NA | NA | unclassified | |
| spondyloarthritides (spa) are a heterogeneous group of hla-b27 associated musculoskeletal diseases that affect the axial and peripheral skeleton and most of them have some extraskeletal manifestations. | |||||||
| 33099652 | HLA-CLASS II (HLA CLASS II) | podoconiosis | African | NA | NA | unclassified | |
| multiplexed gene expression analysis of hla class ii-associated podoconiosis implicates chronic immune activation in its pathogenesis. | |||||||
| 33558538 | HLA-CLASS II (HLA CLASS II) | podoconiosis | Ethiopian | NA | rs9270911 | unclassified | |
| replication of hla class ii locus association with susceptibility to podoconiosis in three ethiopian ethnic groups. | |||||||
| 33558538 | HLA-CLASS II (HLA CLASS II) | podoconiosis | Ethiopian | NA | rs9270911 | unclassified | |
| a previous genome-wide association study (gwas) conducted in the wolaita ethnic group from ethiopia showed association between single nucleotide polymorphisms (snps) in the hla class ii region and podoconiosis. | |||||||
| 33558538 | HLA-CLASS II (HLA CLASS II) | podoconiosis | Ethiopian | NA | rs9270911 | positive | |
| fourteen snps in the hla class ii region showed significant genome-wide association (p < 5.0 x 10-8) with podoconiosis. | |||||||
| 33558538 | HLA (HLA) | podoconiosis | Ethiopian | NA | rs9270911 | unclassified | |
| inclusion of data from the first gwas (combined n = 2289) identified 47 snps in the class ii hla region that were significantly associated with podoconiosis (lead snp also rs9270911 (p = 2.25 x 10-12). | |||||||
| 33558538 | HLA-CLASS II (HLA CLASS II) | podoconiosis | Ethiopian | NA | rs9270911 | unclassified | |
| our findings confirm the hla class ii association with podoconiosis suggesting hla-mediated abnormal induction and regulation of immune responses may have a direct role in its pathogenesis. | |||||||
Copyright 2024