Copyright 2024
| PMID | Allele | Disease | Population | Drug Names | SNP | Class | Sentence |
|---|---|---|---|---|---|---|---|
| 27053962 | HLA-CLASS II (HLA CLASS II) | specific language impairment | NA | NA | NA | unclassified | |
| the protein encoded by this gene is predicted to be a transcription factor based on domain similarities with nfx1, a repressor of hla class ii genes, which have themselves been implicated in specific language impairment. | |||||||
| 34085782 | HUMAN LEUKOCYTE ANTIGEN (HUMAN LEUKOCYTE ANTIGEN) | spastic | NA | NA | NA | unclassified | |
| in this phase i, open-label study, 15 children, aged 1 to 6 years, with moderate to severe spastic cp were treated with a single intravenous infusion of allogeneic human leukocyte antigen (hla) matched or partially matched sibling cb with a cell dose of >=2.5 x 107 cells/kg based on the pre-cryopreservation count (median infused cell dose, 3.3 x 107 ; range, 1.8-5.2 x 107 ). | |||||||
| 24470948 | HUMAN LEUKOCYTE ANTIGEN (HUMAN LEUKOCYTE ANTIGEN) | shingles | NA | NA | NA | unclassified | |
| we analyzed age, sex, and shingles reports; blood levels of cd19+, cd4+, cd8+, and cd56+ mononuclear cells; serum levels of igg subclasses, iga, and igm; and positivity for human leukocyte antigen (hla)-a and -b haplotypes. | |||||||
| 24470948 | HLA-A*01 | shingles | NA | NA | NA | unclassified | |
| patients with shingles reports had greater mean age at diagnosis of cvid/iggsd [54+-13 (standard deviation) years vs. 47+-12 years; p=0.0130] and a greater prevalence of hla-a*01, b*08 positivity (35.5% vs. 17.7%; p=0.0227). | |||||||
| 24470948 | HLA-B*08 | shingles | NA | NA | NA | unclassified | |
| patients with shingles reports had greater mean age at diagnosis of cvid/iggsd [54+-13 (standard deviation) years vs. 47+-12 years; p=0.0130] and a greater prevalence of hla-a*01, b*08 positivity (35.5% vs. 17.7%; p=0.0227). | |||||||
| 24470948 | HLA-A*01 | shingles | NA | NA | NA | positive | |
| hla-a*01, b*08 positivity was also positively associated with shingles reports [p=0.0480; odds ratio 2.61 (1.00, 6.81)]. | |||||||
| 24470948 | HLA-B*08 | shingles | NA | NA | NA | positive | |
| hla-a*01, b*08 positivity was also positively associated with shingles reports [p=0.0480; odds ratio 2.61 (1.00, 6.81)]. | |||||||
| 24470948 | HLA-A*01 | shingles | NA | NA | NA | positive | |
| in conclusion, in white adults at cvid/iggsd diagnosis, age at diagnosis and positivity for hla-a*01, b*08 have significant positive associations with reports of previous shingles. | |||||||
| 24470948 | HLA-B*08 | shingles | NA | NA | NA | positive | |
| in conclusion, in white adults at cvid/iggsd diagnosis, age at diagnosis and positivity for hla-a*01, b*08 have significant positive associations with reports of previous shingles. | |||||||
| 25078879 | HLA-DR (HLA-DR) | cardiac arrest | NA | NA | NA | negative | |
| immune response to tlr ligands in patients after cardiac arrest was generally reduced and associated with lower hla-dr expression. | |||||||
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