HLA Web Resource for SNPs, Populations, Resources, ADRs, Diseases

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PMID Allele Disease Population Drug Names SNP Class Sentence
28476759 HLA (HLA) lamotrigine Chinese Han carbamazepine NA unclassified
NA
28483310 HLA (HLA) stevens-johnson syndrome NA NA NA negation
strong hla-gene associations have been elucidated for specific drug-scar im-adrs such as stevens-johnson syndrome/toxic epidermal necrolysis, although the mechanisms by which carriage of a specific hla allele is necessary but not sufficient for the development of many im-adrs is still being defined.
28553132 HLA-B*15 stevens-johnson syndrome Chinese Han carbamazepine NA unclassified
for example, patients of han-chinese descent carrying the hla-b*1502 allele are at an increased risk of developing stevens-johnson syndrome and toxic epidermal necrolysis (sjs/ten) if given carbamazepine.
28570299 HLA-B*15 stevens-johnson syndrome Indian carbamazepine NA unclassified
hla-a*31: 01 and hla-b*15:02 association with stevens-johnson syndrome and toxic epidermal necrolysis to carbamazepine in a multiethnic malaysian population.
28570299 HLA-A*31 stevens-johnson syndrome Indian carbamazepine NA unclassified
hla-a*31: 01 and hla-b*15:02 association with stevens-johnson syndrome and toxic epidermal necrolysis to carbamazepine in a multiethnic malaysian population.
28570299 HLA-B*15 stevens-johnson syndrome Indian carbamazepine NA unclassified
the majority of the carbamazepine-induced stevens-johnson syndrome and toxic epidermal necrolysis cbz-sjs/ten are associated with hla-b*15:02 in asian populations where this allele is common.
29053440 HLA-B*15 stevens-johnson syndrome Javanese carbamazepine NA unclassified
association of the hla-b alleles with carbamazepine-induced stevens-johnson syndrome/toxic epidermal necrolysis in the javanese and sundanese population of indonesia: the important role of the hla-b75 serotype.
29076187 HLA-B*15 phenytoin South Indian carbamazepine NA unclassified
NA
29076187 HLA-B*15 phenytoin South Indian carbamazepine NA unclassified
NA
29176400 HLA-B*58 allopurinol Malaysian probenecid NA unclassified
NA
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