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| PMID | Allele | Disease | Population | Drug Names | SNP | Class | Sentence |
|---|---|---|---|---|---|---|---|
| 32133321 | HLA-B (HLA-B) | stevens-johnson syndrome | NA | allopurinol | NA | unclassified | |
| allopurinol-induced severe cutaneous adverse reactions (scars) such as stevens-johnson syndrome (sjs), toxic epidermal necrolysis (ten), and drug reaction with eosinophilia and systemic symptoms (dress) syndrome are reportedly associated with the hla-b genotype. | |||||||
| 32133321 | HLA-B (HLA-B) | dress syndrome | NA | allopurinol | NA | unclassified | |
| allopurinol-induced severe cutaneous adverse reactions (scars) such as stevens-johnson syndrome (sjs), toxic epidermal necrolysis (ten), and drug reaction with eosinophilia and systemic symptoms (dress) syndrome are reportedly associated with the hla-b genotype. | |||||||
| 32180714 | HLA-A*31 | stevens-johnson syndrome | Asian | carbamazepine | NA | unclassified | |
| due to genetic differences at population level, drug hypersensitivity reactions are varied, and thus common pharmacogenetics markers for one country might be different from another country, for instance, hla-a*31:01 is associated with carbamazepine (cbz)-induced scars in european and japanese while hla-b*15:02 is associated with cbz-induced stevens-johnson syndrome/toxic epidermal necrolysis (sjs/ten) among taiwanese and southeast asian. | |||||||
| 32180714 | HLA-A*31 | drug hypersensitivity | Asian | carbamazepine | NA | unclassified | |
| due to genetic differences at population level, drug hypersensitivity reactions are varied, and thus common pharmacogenetics markers for one country might be different from another country, for instance, hla-a*31:01 is associated with carbamazepine (cbz)-induced scars in european and japanese while hla-b*15:02 is associated with cbz-induced stevens-johnson syndrome/toxic epidermal necrolysis (sjs/ten) among taiwanese and southeast asian. | |||||||
| 32180714 | HLA-B*15 | stevens-johnson syndrome | Asian | carbamazepine | NA | unclassified | |
| due to genetic differences at population level, drug hypersensitivity reactions are varied, and thus common pharmacogenetics markers for one country might be different from another country, for instance, hla-a*31:01 is associated with carbamazepine (cbz)-induced scars in european and japanese while hla-b*15:02 is associated with cbz-induced stevens-johnson syndrome/toxic epidermal necrolysis (sjs/ten) among taiwanese and southeast asian. | |||||||
| 32180714 | HLA-B*15 | drug hypersensitivity | Asian | carbamazepine | NA | unclassified | |
| due to genetic differences at population level, drug hypersensitivity reactions are varied, and thus common pharmacogenetics markers for one country might be different from another country, for instance, hla-a*31:01 is associated with carbamazepine (cbz)-induced scars in european and japanese while hla-b*15:02 is associated with cbz-induced stevens-johnson syndrome/toxic epidermal necrolysis (sjs/ten) among taiwanese and southeast asian. | |||||||
| 32180714 | HLA ASSOCIATED (HLA-ASSOCIATED) | drug hypersensitivity | Asian | carbamazepine | NA | unclassified | |
| besides the view across the nation, when compared hla alleles from thai population with hla alleles from both european and asian countries, the distribution landscape of hla-associated drug hypersensitivity across many countries could be observed. | |||||||
| 32452529 | HUMAN LEUKOCYTE ANTIGEN (HUMAN LEUKOCYTE ANTIGEN) | stevens-johnson syndrome | Thai | co-trimoxazole | NA | unclassified | |
| this case-control study was conducted to investigate the involvement between genetic variants of human leukocyte antigen (hla) and cyp2c9 in ctx-induced scars, including stevens-johnson syndrome (sjs)/toxic epidermal necrolysis (ten) and drug reaction with eosinophilia and systemic symptoms (dress) in thai patients. | |||||||
| 32452529 | HUMAN LEUKOCYTE ANTIGEN (HUMAN LEUKOCYTE ANTIGEN) | drug reaction with eosinophilia and systemic symptoms | Thai | co-trimoxazole | NA | unclassified | |
| this case-control study was conducted to investigate the involvement between genetic variants of human leukocyte antigen (hla) and cyp2c9 in ctx-induced scars, including stevens-johnson syndrome (sjs)/toxic epidermal necrolysis (ten) and drug reaction with eosinophilia and systemic symptoms (dress) in thai patients. | |||||||
| 32452529 | HLA-A*11 | stevens-johnson syndrome | Thai | co-trimoxazole | NA | positive | |
| in addition, a significant higher frequency of hla-a*11:01-b*15:02 and hla-b*13:01-c*03:04 haplotypes were detected in the group of ctx-induced stevens-johnson syndrome/toxic epidermal necrolysis (sjs/ten) and dress cases, respectively. | |||||||
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