PMID | Allele | Disease | Population | Drug Names | SNP | Class | Sentence |
---|---|---|---|---|---|---|---|
26319500 | HLA-B*15 | stevens-johnson syndrome | Indian | carbamazepine | NA | unclassified | |
carbamazepine-induced stevens-johnson syndrome/ten is strongly associated with the hla-b*1502 allele, which is highly prevalent in han chinese, malay, thai and indian populations. | |||||||
26319500 | HLA-B*15 | adverse drug reaction | Indian | carbamazepine | NA | unclassified | |
prospective screening for the allele may prevent this cutaneous adverse drug reaction from occurring, but many neurologists and other medical practitioners are still unaware of the medico-legal risks of prescribing carbamazepine in susceptible populations and the availability of hla-b*1502 testing. | |||||||
26490229 | HLA-A*31 | rs259945 | Japanese | rs1150738 | rs3869066 | unclassified | |
NA | |||||||
27020614 | HLA-B*15 | stevens-johnson syndrome | Chinese Han | carbamazepine | NA | unclassified | |
the hla-b*15:02 allele in a spanish romani patient with carbamazepine-induced stevens-johnson syndrome. | |||||||
27020614 | HLA-B*15 | stevens-johnson syndrome | Chinese Han | carbamazepine | NA | unclassified | |
the hla-b*15:02 allele is a risk factor for carbamazepine (cbz)-induced stevens-johnson syndrome/toxic epidermal necrolysis in populations where the allele is prevalent. | |||||||
27081535 | HLA-A*02 | stevens-johnson syndrome | Korean | prostaglandin | rs1327464 | unclassified | |
hla-a*02:06 and ptger3 polymorphism exert additive effects in cold medicine-related stevens-johnson syndrome with severe ocular complications. | |||||||
27544047 | HLA-B*15 | stevens-johnson syndrome | Asian | carbamazepine | NA | unclassified | |
validation of a novel real-time pcr assay for detection of hla-b*15:02 allele for prevention of carbamazepine - induced stevens-johnson syndrome/toxic epidermal necrolysis in individuals of asian ancestry. | |||||||
27544047 | HLA-B*15 | stevens-johnson syndrome | Asian | carbamazepine | NA | unclassified | |
sscreening for the hla-b*15:02 allele has been recommended to prevent carbamazepine (cbz) - induced stevens-johnson syndrome (sjs) and toxic epidermal necrolysis (ten) in individuals with asian ancestry. | |||||||
27730770 | HUMAN LEUKOCYTE ANTIGEN (HUMAN LEUKOCYTE ANTIGEN) | stevens-johnson syndrome | NA | oxcarbazepine | NA | unclassified | |
human leukocyte antigen genotyping was performed to detect the genetic predisposition to stevens-johnson syndrome. | |||||||
28205426 | HLA-B*15 | stevens-johnson syndrome | Chinese | carbamazepine | NA | unclassified | |
hla-b*15:02 is a known biomarker for carbamazepine (cbz)-induced stevens-johnson syndrome and toxic epidermal necrolysis (sjs/ten) in some ethnic populations. |
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