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| PMID | Allele | Disease | Population | Drug Names | SNP | Class | Sentence |
|---|---|---|---|---|---|---|---|
| 24285954 | HLA-A*02 | stevens-johnson syndrome | Japanese | NA | NA | only_studied | |
| in silico risk assessment of hla-a*02:06-associated stevens-johnson syndrome and toxic epidermal necrolysis caused by cold medicine ingredients. | |||||||
| 24322785 | HLA-A*31 | stevens-johnson syndrome | Chinese | carbamazepine | NA | unclassified | |
| hla-a*31:01 was reported to be associated with carbamazepine (cbz)-induced severe cutaneous adverse reactions (scar), including drug reaction with eosinophilia and systemic symptoms (dress), stevens-johnson syndrome (sjs) and toxic epidermal necrolysis (ten). | |||||||
| 24322785 | HLA-A*31 | drug reaction with eosinophilia and systemic symptoms | Chinese | carbamazepine | NA | unclassified | |
| hla-a*31:01 was reported to be associated with carbamazepine (cbz)-induced severe cutaneous adverse reactions (scar), including drug reaction with eosinophilia and systemic symptoms (dress), stevens-johnson syndrome (sjs) and toxic epidermal necrolysis (ten). | |||||||
| 24600669 | HLA (HLA) | stevens-johnson syndrome | Asian | carbamazepine | NA | unclassified | |
| human leukocyte-associated antigen (hla) testing is recommended before commencing asian patients on carbamazepine to minimise the risk of stevens-johnson syndrome (sjs). | |||||||
| 24732692 | HLA-B*58 | stevens-johnson syndrome | Thai | allopurinol | NA | positive | |
| stevens-johnson syndrome (sjs) and toxic epidermal necrolysis (ten), caused by allopurinol therapy, are strongly associated with the human leukocyte antigen (hla), hla-b*5801. | |||||||
| 24781922 | HLA-B*44 | stevens-johnson syndrome | Japanese | NA | NA | unclassified | |
| independent strong association of hla-a*02:06 and hla-b*44:03 with cold medicine-related stevens-johnson syndrome with severe mucosal involvement. | |||||||
| 24781922 | HLA-A*02 | stevens-johnson syndrome | Japanese | NA | NA | unclassified | |
| independent strong association of hla-a*02:06 and hla-b*44:03 with cold medicine-related stevens-johnson syndrome with severe mucosal involvement. | |||||||
| 24871931 | HLA-B*15 | phenytoin | British | lamotrigine | NA | positive | |
| NA | |||||||
| 24912294 | HLA-A*31 | stevens-johnson syndrome | NA | NA | NA | unclassified | |
| stevens-johnson syndrome, one of the idiosyncratic adverse effects, may be predicted by the intrinsic hla type (e.g., a*31:01 for cbz). | |||||||
| 25099164 | HLA-B*15 | stevens-johnson syndrome | NA | phenytoin | NA | positive | |
| furthermore, the variant allele hla-b*15:02, encoding human leukocyte antigen, is associated with an increased risk of stevens-johnson syndrome and toxic epidermal necrolysis in response to phenytoin treatment. | |||||||
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