HLA Web Resource for SNPs, Populations, Resources, ADRs, Diseases

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PMID Allele Disease Population Drug Names SNP Class Sentence
12108073 HLA-DR (HLA-DR) septicemia NA NA NA positive+negation
average percentage of cd3+ (69.2 +/- 5.9%), cd4+ (48.9 +/- 10.7%) and hla-dr+ (1.8 +/- 0.9%) lymphocytes and average cd4+/cd8+ ratio (2.97 +/- 1.33) in neonates with septicemia did not significantly differ from average values of these parameters in healthy neonates that were: cd3+ (69.1 +/- 9.0%), cd4+ (47.4 +/- 10.6%), hla-dr+ (1.5 +/- 0.5%) and cd4+/cd8+ (2.29 +/- 1.29).
12875677 HLA IDENTICAL (HLA-IDENTICAL) septicemia NA cyclophosphamide NA unclassified
a patient with saa and pseudomonas aeruginosa septicemia was treated with pbsct from an hla-identical sibling with cyclophosphamide (cy) and total body irradiation (tbi) for conditioning.
12130967 HLA-DR (HLA-DR) ventilator-associated pneumonia NA NA NA negative
the administration of interferon-gamma resulted in the recovery of levels of human leukocyte antigen-dr expression in alveolar macrophages, influenced the inflammatory reaction, and decreased the incidence ventilator-associated pneumonia, without affecting the patients' outcome.
27324766 HLA (HLA) ventilator-associated pneumonia NA NA NA unclassified
a monoclonal antibody targeting hla, medi4893, is in clinical development for the prevention of s. aureus ventilator-associated pneumonia (vap).
12139242 HLA-DQB1 (HLA-DQB1) pyrose NA NA NA unclassified
pyrosequence-based typing of alleles of the hla-dqb1 gene.
12139242 NA (NA) pyrose NA NA NA unclassified
dna typing of alleles of the highly polymorphic hla-dqbi gene was performed by pyrosequencing using purified dna from the 11th international histocompatibility workshop human cell lines and samples from the children's hospital of pittsburgh registry of diabetics and their first-degree relatives.
12139242 HLA-DQB1 (HLA-DQB1) pyrose NA NA NA unclassified
pyrosequencing was optimized for genotyping exon 2 of the hla-dqb1 gene, but the procedure should be applicable to other hla loci.
12139242 HLA-DQB1 (HLA-DQB1) pyrose NA NA NA only_studied
the 61 polymorphic residues of dqb1 exon 2 were identified within four pyrosequencing reactions, obtained by a 70-nucleotide read length in each reaction, in about an hour's time.
12139242 HLA (HLA) pyrose NA NA NA unclassified
pyrosequence-based typing is compatible with genotyping of allelic combinations expected from heterozygous individuals, resulting in nucleotide resolution of the highly polymorphic hla system.
14641938 HLA (HLA) pyrose NA NA NA unclassified
pyrosequencing trade mark : a one-step method for high resolution hla typing.
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