PMID | Allele | Disease | Population | Drug Names | SNP | Class | Sentence |
---|---|---|---|---|---|---|---|
31540313 | HLA-DRB1 (HLA-DRB1) | latent autoimmune diabetes in adults | NA | NA | NA | unclassified | |
hla-dqb1 and hla-drb1 variants confer susceptibility to latent autoimmune diabetes in adults: relative predispositional effects among allele groups. | |||||||
32444887 | HLA (HLA) | latent autoimmune diabetes in adults | Swedish | NA | NA | unclassified | |
we investigated if red meat consumption increases the risk of latent autoimmune diabetes in adults (lada) and t2d, and potential interaction with family history of diabetes (fhd), hla and tcf7l2 genotypes. | |||||||
32835373 | HUMAN LEUKOCYTE ANTIGEN (HUMAN LEUKOCYTE ANTIGEN) | insulin | Norwegian | rs7903146 | rs9939609 | only_studied | |
NA | |||||||
12032378 | HUMAN LEUKOCYTE ANTIGEN (HUMAN LEUKOCYTE ANTIGEN) | late onset diseases | NA | NA | NA | unclassified | |
as well as an expansion in the variety of disorders for which preimplantation genetic diagnosis is offered, new indications have been reported including the use of human leukocyte antigen histocompatibility typing and the application of preimplantation genetic diagnosis to late onset diseases. | |||||||
23085048 | HLA (HLA) | late onset diseases | NA | NA | NA | unclassified | |
in france, the initial indications of pgd have been extended in two directions: on the one hand, to allow identification of a mutation combined with embryo's hla typing, to obtain, at birth, stem cells for therapeutic purposes, and on the other hand, to avoid transmission of late onset diseases without having to test the at-risk parent. | |||||||
15292060 | HLA (HLA) | hyperbilirubinemia | NA | prednisone | NA | unclassified | |
results of a multivariable model showed that treatment was prolonged in patients who received peripheral blood cells, in male patients with female donors, in those with graft-versus-host hla mismatching, and in those with hyperbilirubinemia or multiple sites affected by chronic ghvd at the onset of the disease. | |||||||
15292060 | HLA (HLA) | hyperbilirubinemia | NA | prednisone | NA | positive+negation | |
nonrelapse mortality was increased among patients with hla mismatching or hyperbilirubinemia but not among those with other risk factors associated with prolonged treatment for chronic gvhd. | |||||||
22388280 | NA (NA) | hyperbilirubinemia | Spanish | NA | NA | unclassified | |
in multivariate analysis, the risk factors for marked hyperbilirubinemia after allo-ric were non-hla-identical sibling donors (hazard ratio (hr) 2.2 (95% confidence interval (ci) 1.4-3.6) p=0.001), female donors to male recipients (hr 2.1 (95% ci 1.3-3.3) p=0.003) and high levels of bilirubin and g-glutamyl transpeptidase before transplant (hr 4.5 (95% ci 2.5-8.4) p<0.001 and hr 4.6 (95% ci 2.6-8.1) p<0.001, respectively). | |||||||
22388280 | HLA IDENTICAL (HLA-IDENTICAL) | hyperbilirubinemia | Spanish | NA | NA | unclassified | |
in multivariate analysis, the risk factors for marked hyperbilirubinemia after allo-ric were non-hla-identical sibling donors (hazard ratio (hr) 2.2 (95% confidence interval (ci) 1.4-3.6) p=0.001), female donors to male recipients (hr 2.1 (95% ci 1.3-3.3) p=0.003) and high levels of bilirubin and g-glutamyl transpeptidase before transplant (hr 4.5 (95% ci 2.5-8.4) p<0.001 and hr 4.6 (95% ci 2.6-8.1) p<0.001, respectively). | |||||||
12108073 | HLA-DR (HLA-DR) | septicemia | NA | NA | NA | unclassified | |
[quantitative changes of cd3+, cd4+, cd8+, hla-dr+, t lymphocytes and cd25+ cells in eutrophic full-term neonates with staphylococcal septicemia]. |
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