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| PMID | Allele | Disease | Population | Drug Names | SNP | Class | Sentence |
|---|---|---|---|---|---|---|---|
| 23383350 | HLA-CLASS I (HLA-I) | yellow fever | NA | NA | NA | unclassified | |
| t-cell memory responses elicited by yellow fever vaccine are targeted to overlapping epitopes containing multiple hla-i and -ii binding motifs. | |||||||
| 28975614 | HLA-A*02 | yellow fever | NA | NA | NA | unclassified | |
| here, we studied the tcr repertoire of the hla-a*0201-restricted epitope llwngpmav (hereafter, a2/llw) from yellow fever virus, which generates an immunodominant cd8+ t cell response to the highly effective yf-17d vaccine. | |||||||
| 32645549 | HLA-A*02 | yellow fever | NA | NA | NA | unclassified | |
| the cd8 t cell response to the hla-a2-restricted epitope llwngpmav (llw) of the non-structural protein 4b of yellow fever virus (yfv) is remarkably immunodominant, highly prevalent and powerful in yfv-vaccinated humans. | |||||||
| 32983097 | HLA (HLA) | yellow fever | NA | NA | NA | unclassified | |
| our t cell epitope discovery approach uses a combination of (1) overlapping peptides representing the entire yellow fever virus proteome to search for peptides containing cd4+ and/or cd8+ t cell epitopes, (2) predictors of peptide-hla binding to suggest epitopes and their restricting hla allotypes, (3) generation of peptide-hla tetramers to identify t cell epitopes, and (4) analysis of ex vivo t cell responses to validate the same. | |||||||
| 11895452 | NA (NA) | hyperprolactinaemia | NA | thymidine | NA | negative | |
| hyperprolactinaemia presents in 25% of patients with hf and may reflect decreased activation of t-lymphocytes associated with relatively preserved lv systolic function which is under immune-genetic control at the hla-dq locus. | |||||||
| 16202223 | HLA-DQB1*04 | autoimmune pancreatitis | NA | NA | NA | unclassified | |
| possession of the hla drb1*0405-dqb1*0401 genotype confers a risk for the development of autoimmune pancreatitis. | |||||||
| 16202223 | HLA-DRB1*04 | autoimmune pancreatitis | NA | NA | NA | unclassified | |
| possession of the hla drb1*0405-dqb1*0401 genotype confers a risk for the development of autoimmune pancreatitis. | |||||||
| 17119950 | HLA-DRB1 (HLA-DRB1) | autoimmune pancreatitis | Japanese | NA | NA | unclassified | |
| two critical genes (hla-drb1 and abcf1)in the hla region are associated with the susceptibility to autoimmune pancreatitis. | |||||||
| 17119950 | HLA-DQB1*04 | autoimmune pancreatitis | Japanese | NA | NA | positive | |
| we have previously reported that autoimmune pancreatitis (aip) is a bioclinical entity characterized by high serum immunoglobulin g4 concentrations and association with the hla-drb1*0405-dqb1*0401 haplotype. | |||||||
| 17119950 | HLA-DRB1*04 | autoimmune pancreatitis | Japanese | NA | NA | positive | |
| we have previously reported that autoimmune pancreatitis (aip) is a bioclinical entity characterized by high serum immunoglobulin g4 concentrations and association with the hla-drb1*0405-dqb1*0401 haplotype. | |||||||
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