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PMID Allele Disease Population Drug Names SNP Class Sentence
17446137 HLA (HLA) pyrose NA NA NA unclassified
we hypothesized that pyrosequencing to determine kir-ligand status by direct sequencing of the ligand epitope can be done as an alternative to high-resolution hla-typing.
17446137 HLA (HLA) pyrose NA NA NA unclassified
pyrosequencing is rapid and would be particularly useful in analysis of retrospective cohorts where high-resolution hla-typing is unavailable or too expensive.
17446137 HLA (HLA) pyrose NA NA NA unclassified
primer binding to invariant regions without known snps was critical for kir-ligand assignment by pyrosequencing to be in full concordance with high-resolution hla-typing.
20650293 HLA-CLASS I (HLA CLASS II) pyrose NA NA NA unclassified
a novel single cdna amplicon pyrosequencing method for high-throughput, cost-effective sequence-based hla class i genotyping.
20650293 HLA-CLASS I (HLA CLASS II) pyrose NA NA NA unclassified
we present an assay for sequence-based hla genotyping by titanium read length clonal roche/454 pyrosequencing of a single, universally diagnostic polymerase chain reaction (pcr) amplicon from hla class i cdna that captures most of exons 2, 3, and 4 used for traditional sequence-based typing.
21299525 HLA (HLA) pyrose NA NA NA unclassified
we conclude that clonal pyrosequencing using the gs flx platform and conexio atf software allows reliable identification of hla genotypes at high resolution.
22866951 HLA (HLA) pyrose NA NA NA unclassified
ultra-high resolution hla genotyping and allele discovery by highly multiplexed cdna amplicon pyrosequencing.
22866951 HLA-CLASS I (HLA CLASS II) pyrose NA NA NA unclassified
we designed a cdna amplicon-based pyrosequencing method to capture 94% of the hla class i open-reading-frame with only two amplicons per sample, and an analogous method for class ii hla genes, with a primary focus on sequencing the drb loci.
23274889 HLA (HLA) pyrose NA NA NA unclassified
to exclude secondary effects of diabetes and hla risk genotype on gut microbiota, we compared the intestinal microbiota composition in children with at least two diabetes-associated autoantibodies (n = 18) with autoantibody-negative children matched for age, sex, early feeding history, and hla risk genotype using pyrosequencing.
23775738 HLA (HLA) pyrose NA NA NA unclassified
a total of 14 hla primer pairs with multiplex identifiers (mids) are used in clonal, amplicon-based pyrosequencing of up to 44 samples per plate using the gs flx.
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