Copyright 2024
| PMID | Allele | Disease | Population | Drug Names | SNP | Class | Sentence |
|---|---|---|---|---|---|---|---|
| 22665227 | HLA (HLA) | drug hypersensitivity | NA | NA | NA | unclassified | |
| methods for diagnostic hla typing in disease association and drug hypersensitivity. | |||||||
| 24901010 | HLA (HLA) | drug hypersensitivity | NA | NA | NA | unclassified | |
| hla associations and clinical implications in t-cell mediated drug hypersensitivity reactions: an updated review. | |||||||
| 24901010 | HUMAN LEUKOCYTE ANTIGEN (HUMAN LEUKOCYTE ANTIGEN) | drug hypersensitivity | NA | NA | NA | unclassified | |
| recent advances in pharmacogenetic studies show strong genetic associations between human leukocyte antigen (hla) alleles and susceptibility to drug hypersensitivity. | |||||||
| 24901010 | HLA (HLA) | drug hypersensitivity | NA | NA | NA | unclassified | |
| this review summarizes the literature on recent progresses in pharmacogenetic studies and clinical application of pharmacogenetic screening based on associations between scars and specific hla alleles to avoid serious conditions associated with drug hypersensitivity. | |||||||
| 25965122 | HLA (HLA) | drug hypersensitivity | Chinese | allopurinol | NA | unclassified | |
| pharmacogenomic markers in the hla coding genes have been associated with drug hypersensitivity of multiple drugs, including allopurinol. | |||||||
| 27141480 | HLA-B (HLA-B) | drug hypersensitivity | NA | abacavir | NA | positive+negation | |
| furthermore the t-cell response to altered peptide repertoire model is only shown for abacavir and hla-b(*)57:01 and therefore it may not be generalised to other drug hypersensitivity. | |||||||
| 27720927 | HUMAN LEUKOCYTE ANTIGEN (HUMAN LEUKOCYTE ANTIGEN) | drug hypersensitivity | NA | NA | NA | unclassified | |
| a number of human leukocyte antigen (hla) gene alleles have been found to be genetic risk markers for immunologically mediated drug hypersensitivity. | |||||||
| 29574562 | HLA (HLA) | drug hypersensitivity | NA | NA | NA | unclassified | |
| we review risk factors for developing scar, including hla alleles strongly associated with drug hypersensitivity. | |||||||
| 29651444 | HLA (HLA) | drug hypersensitivity | NA | NA | NA | unclassified | |
| the drug presentation models that explain how small drug antigens might interact with hla and t cell receptor (tcr) molecules in drug hypersensitivity include the hapten theory, the p-i concept, the altered peptide repertoire model, and the altered tcr repertoire model. | |||||||
| 30127801 | HLA (HLA) | allopurinol | Asian | dapsone | NA | unclassified | |
| NA | |||||||
Copyright 2024