Copyright 2024
| PMID | Allele | Disease | Population | Drug Names | SNP | Class | Sentence |
|---|---|---|---|---|---|---|---|
| 18345414 | HLA-DQB1*06 | migraine without aura | NA | melatonin | NA | negation | |
| we analyzed the presence of hla dqb1*0602 allele in 50 healthy subjects with no history of migraine, 53 patients with migraine without aura and 52 patients with migraine with aura. | |||||||
| 18345414 | HLA-DQB1*06 | migraine | NA | melatonin | NA | unclassified | |
| prevalence of hla dqb1*0602 allele in patients with migraine. | |||||||
| 18345414 | HLA-DRB1 (HLA-DRB1) | migraine | NA | melatonin | NA | unclassified | |
| an increase in the hla-drb1 allele frequency in patients with visual aura has raised greater awareness of the genetic background in migraine.purposesince the regions dr and dq of the hla are in tightly linkage desiquilibrium we hypothesize that hla-dqb1*0602 might be associated to the pathophysiology of migraine. | |||||||
| 18345414 | HLA-DQB1*06 | migraine | NA | melatonin | NA | unclassified | |
| an increase in the hla-drb1 allele frequency in patients with visual aura has raised greater awareness of the genetic background in migraine.purposesince the regions dr and dq of the hla are in tightly linkage desiquilibrium we hypothesize that hla-dqb1*0602 might be associated to the pathophysiology of migraine. | |||||||
| 16362659 | HLA-DRB1 (HLA-DRB1) | migraine without aura | Italian | NA | NA | positive | |
| when the patients were divided into disease subgroups (migraine with and without aura), hla-drb1**16 allele was significantly increased (p<0.05) only in migraine without aura patients. | |||||||
| 16362659 | HLA-DRB1 (HLA-DRB1) | migraine | Italian | NA | NA | unclassified | |
| association between migraine and hla-drb1 gene polymorphisms. | |||||||
| 16362659 | HLA-DRB1 (HLA-DRB1) | migraine | Italian | NA | NA | only_studied | |
| we examined the distribution of hla-drb1 alleles in a cohort of 255 italian migraine patients and in a control group of 325 healthy subjects. | |||||||
| 16362659 | HLA-DRB1*12 | migraine | Italian | NA | NA | lack_of_evidence | |
| the frequency of drb1*12 allele was found to be significantly reduced (p=0.02) in patients with migraine while the drb1*16 allele was significantly increased (p=0.04) in comparison with controls. | |||||||
| 16362659 | HLA-DRB1*16 | migraine | Italian | NA | NA | lack_of_evidence | |
| the frequency of drb1*12 allele was found to be significantly reduced (p=0.02) in patients with migraine while the drb1*16 allele was significantly increased (p=0.04) in comparison with controls. | |||||||
| 16362659 | HLA-DRB1 (HLA-DRB1) | migraine | Italian | NA | NA | unclassified | |
| we conclude that, in italian patients, migraine is associated with different alleles of the hla-drb1 locus. | |||||||
Copyright 2024