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| PMID | Allele | Disease | Population | Drug Names | SNP | Class | Sentence |
|---|---|---|---|---|---|---|---|
| 20149831 | HLA-DRB1 (HLA-DRB1) | recurrent miscarriage | Caucasian | NA | NA | unclassified | |
| study of the structure and impact of human leukocyte antigen (hla)-g-a, hla-g-b, and hla-g-drb1 haplotypes in families with recurrent miscarriage. | |||||||
| 20149831 | HLA-G (HLA-G) | recurrent miscarriage | Caucasian | NA | NA | positive | |
| carriage of the g14bp ins is associated with low levels of soluble hla-g and increases the risk of recurrent miscarriage (rm). | |||||||
| 20307907 | HLA-CLASS II (HLA CLASS II) | recurrent miscarriage | NA | NA | NA | unclassified | |
| our knowledge primarily comes from studies of the impact on pregnancy outcome of hla class ii alleles known to restrict cd4 t cell mediated anti-hy responses among 358 secondary recurrent miscarriage (srm) patients and 203 of their children born prior to the miscarriages and investigation of these hla alleles in 8 patients with recurrent severe placental abruptions. | |||||||
| 20307907 | HLA-CLASS II (HLA CLASS II) | placental abruptions | NA | NA | NA | unclassified | |
| our knowledge primarily comes from studies of the impact on pregnancy outcome of hla class ii alleles known to restrict cd4 t cell mediated anti-hy responses among 358 secondary recurrent miscarriage (srm) patients and 203 of their children born prior to the miscarriages and investigation of these hla alleles in 8 patients with recurrent severe placental abruptions. | |||||||
| 20307907 | HLA (HLA) | placental abruptions | NA | NA | NA | unclassified | |
| most patients with recurrent placental abruptions had firstborn boys and significantly more of these patients carried hla haplotypes with hy-restricting class ii alleles compared with controls (p=0.009). | |||||||
| 20395221 | HLA-CLASS II (HLA CLASS II) | recurrent miscarriage | NA | NA | NA | negative | |
| the chance of a live birth after a diagnosis of secondary recurrent miscarriage (srm) is reduced in patients who, prior to the miscarriages, gave birth to a boy and carry hla class ii alleles that efficiently present male-specific (h-y) antigens to the immune system. | |||||||
| 20403270 | HLA-DRB1*03 | recurrent miscarriage | NA | NA | NA | positive | |
| in women with secondary recurrent miscarriage, the hla-drb1*03 allele or homozygocity for a hla-g14 basepair insertion is more frequent than in controls. | |||||||
| 20605049 | HLA (HLA) | recurrent miscarriage | NA | NA | NA | negative | |
| the presence of hla-antibodies in recurrent miscarriage patients is associated with a reduced chance of a live birth. | |||||||
| 20605049 | HLA (HLA) | recurrent miscarriage | NA | NA | NA | unclassified | |
| anti-paternal hla-antibodies are considered a harmless phenomenon during most pregnancies, whereas their role in recurrent miscarriage (rm) patients is disputed. | |||||||
| 21075157 | HUMAN LEUKOCYTE ANTIGEN (HUMAN LEUKOCYTE ANTIGEN) | recurrent miscarriage | NA | NA | NA | negation | |
| prevalence and qualitative properties of circulating anti-human leukocyte antigen alloantibodies after pregnancy: no association with unexplained recurrent miscarriage. | |||||||
Copyright 2024