Copyright 2024
| PMID | Allele | Disease | Population | Drug Names | SNP | Class | Sentence |
|---|---|---|---|---|---|---|---|
| 25700963 | HLA (HLA) | recurrent miscarriage | NA | NA | NA | unclassified | |
| hla associations and hla sharing in recurrent miscarriage: a systematic review and meta-analysis. | |||||||
| 25700963 | HLA (HLA) | recurrent miscarriage | NA | NA | NA | unclassified | |
| problemthe aim of this meta-analysis was to evaluate whether specific maternal hla alleles and hla sharing of couples are associated with the occurrence of recurrent miscarriage (rm). | |||||||
| 25827646 | HUMAN LEUKOCYTE ANTIGEN (HUMAN LEUKOCYTE ANTIGEN) | recurrent miscarriage | NA | NA | NA | unclassified | |
| insufficient invasion of the uterine lining by invading extravillous trophoblast is the primary defect in pregnancy disorders such as recurrent miscarriage, and this process is regulated by interaction between maternal killer immunoglobulin-like receptors (kirs) expressed by the uterine natural killer cells and their ligand human leukocyte antigen (hla)-c expressed by extravillous trophoblast. | |||||||
| 25827646 | HLA-C (HLA-C) | recurrent miscarriage | NA | NA | NA | unclassified | |
| these insights could have an impact on the selection of single embryo transfer and/or oocyte/sperm donor according to hla-c in patients with recurrent miscarriage or recurrent implantation failure and a kir aa haplotype. | |||||||
| 27172837 | HLA-C (HLA-C) | recurrent miscarriage | NA | NA | NA | unclassified | |
| hla-c antibodies in women with recurrent miscarriage suggests that antibody mediated rejection is one of the mechanisms leading to recurrent miscarriage. | |||||||
| 27172837 | HLA-C (HLA-C) | recurrent miscarriage | NA | NA | NA | unclassified | |
| therefore, this study hypothesize that antibodies against hla-c may play a role in the occurrence of unexplained consecutive recurrent miscarriage. | |||||||
| 27172837 | HLA-C (HLA-C) | recurrent miscarriage | NA | NA | NA | positive | |
| although in general a higher incidence of hla antibodies was found in women with recurrent miscarriage 31.6% vs. in control subjects 9.5% (adjusted or 4.3, 95% ci 2.0-9.5), the contribution of antibodies against hla-c was significantly higher in women with recurrent miscarriage (9.5%) compared to women with uneventful pregnancy (1%) (adjusted or 11.0, 95% ci 1.3-89.0). | |||||||
| 27172837 | HLA-C (HLA-C) | recurrent miscarriage | NA | NA | NA | unclassified | |
| in contrast to the control group, hla-c antibodies in the recurrent miscarriage group were more often able to bind complement. | |||||||
| 27172837 | HLA-C (HLA-C) | recurrent miscarriage | NA | NA | NA | positive | |
| the higher incidence of antibodies specific for hla-c in women with recurrent miscarriage suggests that hla-c antibodies may be involved in the aetiology of unexplained consecutive recurrent miscarriage. | |||||||
| 27525330 | HLA-G (HLA-G) | recurrent miscarriage | NA | NA | NA | unclassified | |
| frequency of null allele of human leukocyte antigen-g (hla-g) locus in subjects to recurrent miscarriage. | |||||||
Copyright 2024