Copyright 2024
| PMID | Allele | Disease | Population | Drug Names | SNP | Class | Sentence |
|---|---|---|---|---|---|---|---|
| 15070884 | NA (NA) | recurrent miscarriage | NA | NA | NA | unclassified | |
| a study of hla-dr and -dq alleles in 588 patients and 562 controls confirms that hla-drb1*03 is associated with recurrent miscarriage. | |||||||
| 15070884 | HLA-DRB1*01 | recurrent miscarriage | NA | NA | NA | unclassified | |
| previous studies have demonstrated an association between recurrent miscarriage (rm) and the maternal hla-drb1*01 and -drb1*03 alleles. | |||||||
| 15070884 | HLA-DRB1*03 | recurrent miscarriage | NA | NA | NA | unclassified | |
| previous studies have demonstrated an association between recurrent miscarriage (rm) and the maternal hla-drb1*01 and -drb1*03 alleles. | |||||||
| 15191524 | HLA-G (HLA-G) | recurrent miscarriage | NA | NA | NA | lack_of_evidence | |
| the hla-g genotype, homozygous for the presence of the 14 bp sequence in exon 8, was significantly associated with reduced fertility with respect to unsuccessful ivf treatments and increased risk of recurrent miscarriage (combined p < 0.01). | |||||||
| 16052406 | HLA-G (HLA-G) | recurrent miscarriage | NA | NA | NA | unclassified | |
| the inherited thrombophilia, gene polymorphisms of coagulation and anticoagulation factor such as thrombomodulin, endothelial protein c receptor, plasminogen activator inhibitor 1, and factor xiii; human lymphocyte antigen (hla-g); detoxification enzymes (glutathione- s-transferase m1); cytokines such as interleukin (il) -1 and il-6; hormones (cyp17); vasodilators (nitric oxide synthase 3); and vitamins (transcobalamin) are involved in the pathogenesis of sporadic and recurrent miscarriage. | |||||||
| 16052406 | HLA-G (HLA-G) | thrombophilia | NA | NA | NA | unclassified | |
| the inherited thrombophilia, gene polymorphisms of coagulation and anticoagulation factor such as thrombomodulin, endothelial protein c receptor, plasminogen activator inhibitor 1, and factor xiii; human lymphocyte antigen (hla-g); detoxification enzymes (glutathione- s-transferase m1); cytokines such as interleukin (il) -1 and il-6; hormones (cyp17); vasodilators (nitric oxide synthase 3); and vitamins (transcobalamin) are involved in the pathogenesis of sporadic and recurrent miscarriage. | |||||||
| 16122986 | HLA-CLASS II (HLA CLASS II) | recurrent miscarriage | Japanese | NA | NA | unclassified | |
| molecular genetic studies on the compatibility of hla class ii alleles in patients with unexplained recurrent miscarriage in the japanese population. | |||||||
| 16122986 | HLA (HLA) | recurrent miscarriage | Japanese | NA | NA | unclassified | |
| it is hypothesized that patients having unexplained recurrent miscarriage lack an appropriate immune reaction against their partner's antigens, which means possible compatibility of hla antigens between the patient couples. | |||||||
| 16122986 | HLA-CLASS II (HLA CLASS II) | recurrent miscarriage | Japanese | NA | NA | unclassified | |
| in conclusion, it is suggested that the compatibility of hla class ii antigens between couples might be involved in the genesis of unexplained recurrent miscarriage. | |||||||
| 16514201 | HLA-E (HLA-E) | recurrent miscarriage | NA | NA | NA | unclassified | |
| comparison of the expression of human leukocyte antigen (hla)-g and hla-e in women with normal pregnancy and those with recurrent miscarriage. | |||||||
Copyright 2024