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PMID Allele Disease Population Drug Names SNP Class Sentence
21933399 HLA-DR3 (BROAD ANTIGEN) severe sepsis NA NA NA unclassified
receiver operating characteristic (roc) curves were plotted to measure the performance and discriminating threshold of dmhla-dr3, dmhla-dr7, dmhla-dr7-3, mhla-dr0, mhla-dr3 and mhla-dr7 in predicting mortality of severe sepsis.
21933399 HLA-DRB1*07 severe sepsis NA NA NA unclassified
roc curve analysis showed that dmhla-dr3 and dmhla-dr7 were reliable indicators of mortality in severe sepsis.
21933399 HLA-DR3 (BROAD ANTIGEN) severe sepsis NA NA NA unclassified
roc curve analysis showed that dmhla-dr3 and dmhla-dr7 were reliable indicators of mortality in severe sepsis.
21933399 HLA-DR (HLA-DR) severe sepsis NA NA NA unclassified
the change of mhla-dr over time may be a reliable predictor for mortality in patients with severe sepsis.
21939530 HLA-DR (HLA-DR) severe sepsis NA NA NA positive
serial increase of il-12 response and human leukocyte antigen-dr expression in severe sepsis survivors.
21939530 HLA-DR (HLA-DR) severe sepsis NA NA NA unclassified
we designed this prospective observational study to measure monocyte human leukocyte antigen (hla)-dr expression, plasma cytokine levels and cytokine responses on days 1 and 7 in stimulated peripheral blood mononuclear cells (pbmcs) of healthy controls and patients with severe sepsis.
21939530 HUMAN LEUKOCYTE ANTIGEN (HUMAN LEUKOCYTE ANTIGEN) severe sepsis NA NA NA unclassified
we designed this prospective observational study to measure monocyte human leukocyte antigen (hla)-dr expression, plasma cytokine levels and cytokine responses on days 1 and 7 in stimulated peripheral blood mononuclear cells (pbmcs) of healthy controls and patients with severe sepsis.
21939530 HLA-DR (HLA-DR) severe sepsis NA NA NA unclassified
monocyte hla-dr expression and il-12 response from pbmcs are restored in patients who survive severe sepsis.
22011628 HLA-DR (HLA-DR) severe sepsis NA NA NA only_studied
herein, novel perspectives regarding monocyte hla-dr assessed as a dynamic parameter in septic patients will be discussed in the context of a recently published study investigating daily evolution of monocyte hla-dr with regard to 28 day-mortality after severe sepsis.
23660098 HLA-DR (HLA-DR) severe sepsis NA NA NA unclassified
uti can decrease in the expression of treg and th17, inverse the ratio of treg/th17, decrease in the expression of il-17, il-6 and il-10, ameliorate the immune status, and improve the expression of hla-dr. uti is expected to improve the prognosis of patients with severe sepsis.
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