Copyright 2024
| PMID | Allele | Disease | Population | Drug Names | SNP | Class | Sentence |
|---|---|---|---|---|---|---|---|
| 19620056 | HLA-DR (HLA-DR) | severe sepsis | NA | NA | NA | positive | |
| the levels of hla-dr were significantly increased in severe sepsis patients with 2-4 dysfunctional organs and marshall score of 5-12 (p<0.05 or p<0.001). | |||||||
| 19620056 | HLA-DR (HLA-DR) | severe sepsis | NA | NA | NA | negation | |
| no changes in hla-dr levels in severe sepsis patients with 5-6 dysfunctional organs and marshall scores of 13-22. | |||||||
| 19620056 | HLA-DR (HLA-DR) | severe sepsis | NA | NA | NA | unclassified | |
| in patients with severe sepsis, persistent low cd(14)(+) monocyte hla-dr levels predicts high mortality. | |||||||
| 21153402 | HLA-DR (HLA-DR) | severe sepsis | NA | NA | NA | unclassified | |
| purposeimmunoparalysis defined by prolonged monocyte human leukocyte antigen dr depression is associated with adverse outcomes in adult severe sepsis and can be reversed with granulocyte macrophage colony-stimulating factor (gm-csf). | |||||||
| 21933399 | HLA-DR (HLA-DR) | severe sepsis | NA | NA | NA | unclassified | |
| changes of monocyte human leukocyte antigen-dr expression as a reliable predictor of mortality in severe sepsis. | |||||||
| 21933399 | HLA-DR (HLA-DR) | severe sepsis | NA | NA | NA | negation | |
| on the contrary, other studies found mhla-dr was not a useful prognostic marker in severe sepsis. | |||||||
| 21933399 | HLA-DR (HLA-DR) | severe sepsis | NA | NA | NA | unclassified | |
| the objective of this study was to estimate the prognostic value of changes of mhla-dr to predict mortality in severe sepsis. | |||||||
| 21933399 | HLA-DR (HLA-DR) | severe sepsis | NA | NA | NA | unclassified | |
| in this prospective observational study, mhla-dr was measured by flow cytometry in peripheral blood from 79 adult patients with severe sepsis. | |||||||
| 21933399 | HLA-DR (HLA-DR) | severe sepsis | NA | NA | NA | unclassified | |
| mhla-dr levels were determined on day 0, 3, 7 after admission to the surgical intensive care unit (sicu) with a diagnosis of severe sepsis. | |||||||
| 21933399 | HLA-DRB1*07 | severe sepsis | NA | NA | NA | unclassified | |
| receiver operating characteristic (roc) curves were plotted to measure the performance and discriminating threshold of dmhla-dr3, dmhla-dr7, dmhla-dr7-3, mhla-dr0, mhla-dr3 and mhla-dr7 in predicting mortality of severe sepsis. | |||||||
Copyright 2024