PMID | Allele | Disease | Population | Drug Names | SNP | Class | Sentence |
---|---|---|---|---|---|---|---|
7940354 | HLA (HLA) | prolapses | NA | NA | NA | unclassified | |
the clinico-immunogenetic analysis of 47 patients with marfan's syndrome and 83 patients with chest deformities combined with valvular prolapses and other connective tissues dysplasias elucidated a close relation of hla-antigens allele variants with clinical dysplasia variants and specific immune alterations. | |||||||
11285404 | HLA-DR (HLA-DR) | dermatofibromas | NA | NA | NA | unclassified | |
twenty-seven jxg, ten dermatofibromas (df), and ten age-matched normal skin specimens were stained using standard immunohistochemistry methods, and all jxgs were fascin+ and cd68+, although 26 of 27 were reactive for hla-dr, 25 of 27 for factor xiiia, 25 of 27 for lca, 21of 27 for cd4, and 8 of 27 for polyclonal s100. | |||||||
11285404 | HLA-DR (HLA-DR) | dermatofibromas | NA | NA | NA | unclassified | |
eight of ten dermatofibromas were fxiiia+; all were negative for hla-dr, lca, cd4, and polyclonal s100. | |||||||
8884646 | HLA-DQB1 (HLA-DQB1) | early-onset periodontitis | Japanese | glycine | NA | unclassified | |
hla class ii genotypes associated with early-onset periodontitis: dqb1 molecule primarily confers susceptibility to the disease. | |||||||
8884646 | HLA-DRB1 (HLA-DRB1) | early-onset periodontitis | Japanese | glycine | NA | unclassified | |
dna typing was performed on 24 japanese patients with early-onset periodontitis (eop) using the pcr-rflp method to investigate an association of the susceptibility to eop with the particular hla class ii alleles (hla-drb1, -dqa1, and -dqb1). | |||||||
8884646 | HLA-DQA1*01 | early-onset periodontitis | Japanese | glycine | NA | unclassified | |
dna typing was performed on 24 japanese patients with early-onset periodontitis (eop) using the pcr-rflp method to investigate an association of the susceptibility to eop with the particular hla class ii alleles (hla-drb1, -dqa1, and -dqb1). | |||||||
8884646 | HLA-DQB1 (HLA-DQB1) | early-onset periodontitis | Japanese | glycine | NA | unclassified | |
dna typing was performed on 24 japanese patients with early-onset periodontitis (eop) using the pcr-rflp method to investigate an association of the susceptibility to eop with the particular hla class ii alleles (hla-drb1, -dqa1, and -dqb1). | |||||||
10488751 | HLA-DQB1 (HLA-DQB1) | early-onset periodontitis | Japanese | NA | NA | negation | |
no association with hla-dqb1 in european caucasians with early-onset periodontitis. | |||||||
10488751 | HLA-DQB1 (HLA-DQB1) | early-onset periodontitis | Japanese | NA | NA | unclassified | |
a recent report of a japanese population found an association between an atypical bamhi site in the hla-dqb1 gene and a severe form of early-onset periodontitis (eop). | |||||||
7914843 | HLA-DR (HLA-DR) | scrub typhus | NA | NA | NA | lack_of_evidence | |
hla-dr+cd3+ and cd8+ cells are increased but cd4+cd45ra+ cells are reduced in the peripheral blood in human scrub typhus. |
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