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PMID Allele Disease Population Drug Names SNP Class Sentence
29259327 HLA-A*02 scrub typhus NA NA NA unclassified
finally, we identified hla-a*0201-restricted and highly conserved cd8 t-cell epitopes in the tsa56 antigen, which may be valuable tools for assessing cellular immunity against o. tsutsugamushi and developing an effective scrub typhus vaccine.
23953920 HUMAN LEUKOCYTE ANTIGEN (HUMAN LEUKOCYTE ANTIGEN) acute lung injury NA NA NA unclassified
we performed a retrospective, single-center cohort study and identified cases of acute amr based on the presence of circulating donor-specific human leukocyte antigen (hla) antibodies (dsa), histologic evidence of acute lung injury, c4d deposition and clinical allograft dysfunction.
7924371 HLA-DR (HLA-DR) severe sepsis NA NA NA lack_of_evidence
monocyte hla-dr expression, significantly decreased in patients with severe sepsis, was correlated both with il-6 (p < .005) and il-8 concentrations (p < .001).
11497155 HLA-DR (HLA-DR) severe sepsis NA NA NA unclassified
thirty-five patients admitted with severe sepsis.measurementsanalysis of peripheral blood on admission and 48 h later of the absolute white cell count and the immunophenotype of lymphocyte (cd3, cd3-hladr, cd4, cd8, cd4/cd8 ratio, cd19, and cd25) and monocyte (cd13, cd13-hladr, cd14, cd14-hladr, cd13-cd14, and cd4) subpopulations.
11497155 HLA-DR (HLA-DR) severe sepsis NA NA NA positive
a single blood sample test obtaining the absolute monocyte and cd13-hladr subpopulation count in the first days of admission could contribute to simplifying the classification of patients with severe sepsis into high- and low-mortality risk.
12595977 HLA-DR (HLA-DR) severe sepsis NA NA NA only_studied
to evaluate the effect of recombinant human granulocyte-macrophage colony-stimulating factor (rhgm-csf) on immunoparalysis as defined by a sustained decrease of hla-dr expression on monocytes in patients with severe sepsis.designprospective, non-randomised observational study.
12595977 HLA-DR (HLA-DR) severe sepsis NA NA NA unclassified
nine consecutive patients with severe sepsis and a documented hla-dr expression on peripheral monocytes of less than 150 mean fluorescence intensity (mfi) over a period of at least 48 h prior to intervention.measurements and mean mfi was 69.4+/-13.2 24 h before and 56.7+/-8.2 on the day of the administration of 5 micro g/kg rhgm-csf.
19620056 HLA-DR (HLA-DR) severe sepsis NA NA NA unclassified
[human leucocyte antigen-dr expression on cd(14)(+) monocytes and its relationships with multiple organ dysfunction syndrome in severe sepsis].
19620056 HLA-DR (HLA-DR) severe sepsis NA NA NA unclassified
to explore the changes of cd(14)(+) monocyte human leucocyte antigen dr (hla-dr) and their relationship with multiple organ dysfunction syndrome (mods) in severe sepsis.
19620056 HLA-DR (HLA-DR) multiple organ dysfunction syndrome NA NA NA unclassified
to explore the changes of cd(14)(+) monocyte human leucocyte antigen dr (hla-dr) and their relationship with multiple organ dysfunction syndrome (mods) in severe sepsis.
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