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PMID Allele Disease Population Drug Names SNP Class Sentence
22701553 HLA (HLA) acute kidney injury NA NA NA unclassified
a multicentre study of acute kidney injury in severe sepsis and septic shock: association with inflammatory phenotype and hla genotype.
22701553 HLA (HLA) severe sepsis NA NA NA only_studied
to investigate the association between severity of acute kidney injury (aki) and outcome, systemic inflammatory phenotype and hla genotype in severe sepsis.
22701553 HLA (HLA) acute kidney injury NA NA NA only_studied
to investigate the association between severity of acute kidney injury (aki) and outcome, systemic inflammatory phenotype and hla genotype in severe sepsis.
23891702 HLA-DR (HLA-DR) septic shock NA NA NA unclassified
effects of corticotropin-releasing hormone on proopiomelanocortin derivatives and monocytic hla-dr expression in patients with septic shock.
23891702 HLA-DR (HLA-DR) septic shock NA NA NA negative
from the correlation between plasma concentration of a-msh and mhla-dr expression, we conclude that in patients with septic shock the down-regulation of mhal-dr expression is accompanied by the loss of monocytic release of a-msh into the cardiovascular compartment.
28072859 HLA-DR (HLA-DR) septic shock NA NA NA positive
a decrease of tcr diversity and monocyte hla-dr expression were observed in the early stage of septic shock, while cd4+ t cells displayed an increase of pd-1 expression.
32188504 HLA-DR (HLA-DR) septic shock NA NA NA unclassified
we used a high-density microarray and rt-qpcr to evaluate the herv and mammalian apparent long terminal repeat retrotransposons (malr) transcriptome in a pilot study that included 20 selected septic shock patients, stratified on mhla-dr expression, with samples collected on day 1 and day 3 after inclusion.
32188504 HLA-DR (HLA-DR) septic shock NA NA NA unclassified
we provided evidence that a subset of herv/malr and conventional genes were differentially expressed in septic shock patients, according to their immune status, using monocyte hla-dr (mhla-dr) expression as a proxy.
32691839 HLA-DR (HLA-DR) septic shock NA NA NA only_studied
then the tool was clinically assessed using samples from 10 healthy volunteers and 20 septic shock patients stratified using human leukocyte antigen-dr expression on monocytes (mhla-dr).
32691839 HLA-DR (HLA-DR) septic shock NA NA NA unclassified
the clinical assessment of the ipp markers demonstrated various gene modulations that could distinctly differentiate 3 profiles: healthy volunteers, intermediate mhla-dr septic shock patients, and low mhla-dr septic shock patients.
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