Copyright 2024
| PMID | Allele | Disease | Population | Drug Names | SNP | Class | Sentence |
|---|---|---|---|---|---|---|---|
| 25324403 | HUMAN LEUKOCYTE ANTIGEN (HUMAN LEUKOCYTE ANTIGEN) | epithelial ovarian cancer | NA | NA | NA | unclassified | |
| prognostic impact of human leukocyte antigen class i expression and association of platinum resistance with immunologic profiles in epithelial ovarian cancer. | |||||||
| 15566505 | HLA-DR (HLA-DR) | fulminant hepatitis | NA | NA | NA | unclassified | |
| in fulminant hepatitis, an increased population of human leukocyte antigen (hla)-dr(+) cd8(+) lymphocytes was observed in peripheral blood by flow cytometry, which was accompanied by the presence of hla-dr(hi) lymphocytes. | |||||||
| 7689946 | HLA-DR (HLA-DR) | septic shock | NA | NA | NA | unclassified | |
| monocytes from septic shock patients had significantly less hla-dr expression than normal subjects and there was a trend toward a lower proportion of gated monocytes that expressed cd14 in septic shock patients. | |||||||
| 7689946 | HLA-DR (HLA-DR) | septic shock | NA | NA | NA | positive+negation | |
| septic shock patients had no significant increases in il-2r or hla-dr expression on cd3 lymphocytes compared with control subjects, but they had significantly lower numbers of total, cd3, cd4, and cd8 lymphocytes and a higher prevalence of anergy. | |||||||
| 8960643 | HLA-DR (HLA-DR) | acetate | NA | prostaglandin | NA | lack_of_evidence | |
| NA | |||||||
| 10695660 | HLA-DR (HLA-DR) | septic shock | NA | NA | NA | negative | |
| decreased monocyte responsiveness to bacterial toxins and decreased expression of human-leukocyte-associated antigen-dr (hla-dr) have been reported during septic shock and critical illness. | |||||||
| 10695660 | HLA-DR (HLA-DR) | critical illness | NA | NA | NA | negative | |
| decreased monocyte responsiveness to bacterial toxins and decreased expression of human-leukocyte-associated antigen-dr (hla-dr) have been reported during septic shock and critical illness. | |||||||
| 12847405 | HLA-DR (HLA-DR) | septic shock | NA | NA | NA | unclassified | |
| in patients with septic shock (mortality rate at 28 days, 56%; mean admission simplified acute physiology score ii, 47), we first illustrated immunoparalysis by showing a severe diminished monocytic human leukocyte antigen (hla)-dr expression. | |||||||
| 12847405 | HUMAN LEUKOCYTE ANTIGEN (HUMAN LEUKOCYTE ANTIGEN) | septic shock | NA | NA | NA | unclassified | |
| in patients with septic shock (mortality rate at 28 days, 56%; mean admission simplified acute physiology score ii, 47), we first illustrated immunoparalysis by showing a severe diminished monocytic human leukocyte antigen (hla)-dr expression. | |||||||
| 12888330 | HLA-DR3 (BROAD ANTIGEN) | septic shock | NA | NA | NA | negation | |
| a linkage disequilibrium between tnf2 allele and hla-dr3 was seen, this haplotype was not associated with severity of acute pancreatitis or outcome of septic shock in asp patients. | |||||||
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