Copyright 2024
| PMID | Allele | Disease | Population | Drug Names | SNP | Class | Sentence |
|---|---|---|---|---|---|---|---|
| 12888330 | HLA-DR3 (BROAD ANTIGEN) | acute pancreatitis | NA | NA | NA | negation | |
| a linkage disequilibrium between tnf2 allele and hla-dr3 was seen, this haplotype was not associated with severity of acute pancreatitis or outcome of septic shock in asp patients. | |||||||
| 12915353 | HLA-DR (HLA-DR) | septic shock | NA | NA | NA | unclassified | |
| [preliminary results in standardization of flow cytometry protocols for monocytic hla-dr measurement and their application in the follow up of septic shock]. | |||||||
| 12915353 | HLA-DR (HLA-DR) | septic shock | NA | NA | NA | unclassified | |
| in septic shock, the diminished hla-dr expression on monocytes has been proposed as a marker of immunoparalysis that correlates with an increased risk for fatal outcome. | |||||||
| 12915353 | HLA-DR (HLA-DR) | septic shock | NA | NA | NA | unclassified | |
| hla-dr measurement on monocytes was determined by means of flow cytometry in 54 healthy donors and 16 patients with septic shock. | |||||||
| 12915353 | HLA-DR (HLA-DR) | septic shock | NA | NA | NA | negative | |
| at 48 hours after diagnosis of septic shock, we found severely decreased percentages of monocytes expressing hla-dr in septic patients (24 +/- 4%, mean +/- sem) in comparison with healthy donors (90 +/- 1%), p < 0.001). | |||||||
| 12915353 | HLA-DR (HLA-DR) | septic shock | NA | NA | NA | unclassified | |
| this study illustrates the state of immunoparalysis in patients with septic shock and supports the potential interest in measuring hla-dr expression on monocytes. | |||||||
| 16352967 | HLA-DR (HLA-DR) | septic shock | NA | NA | NA | lack_of_evidence | |
| combined with a reduced percentage of monocytes expressing human leukocyte antigen-dr, a reduced cd3 expression may be involved in the failure of antigen presentation depicted after septic shock, whereas the diminished percentage of circulating gammadelta t cells could be partly responsible for the elevated incidence of secondary infections. | |||||||
| 16352967 | HLA-DR (HLA-DR) | secondary infections | NA | NA | NA | lack_of_evidence | |
| combined with a reduced percentage of monocytes expressing human leukocyte antigen-dr, a reduced cd3 expression may be involved in the failure of antigen presentation depicted after septic shock, whereas the diminished percentage of circulating gammadelta t cells could be partly responsible for the elevated incidence of secondary infections. | |||||||
| 16741700 | HLA-DR (HLA-DR) | septic shock | NA | NA | NA | unclassified | |
| persisting low monocyte human leukocyte antigen-dr expression predicts mortality in septic shock. | |||||||
| 16741700 | HLA-DR (HLA-DR) | septic shock | NA | NA | NA | only_studied | |
| we assessed whether a low monocyte human leukocyte antigen-dr (mhla-dr) expression, proposed as a marker of immunosuppression, is an independent predictor of mortality in patients who survived the initial 48 h of septic shock.design and prospective observational study performed in two adult intensive care units at a university hospital. | |||||||
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