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PMID Allele Disease Population Drug Names SNP Class Sentence
33813808 HLA-DR (HLA-DR) septic shock NA polymyxin NA unclassified
pmx-dhp improved monocyte human leukocyte antigen-dr expression in patients with severe sepsis and septic shock.
33813808 HLA-DR (HLA-DR) severe sepsis NA polymyxin NA unclassified
pmx-dhp improved monocyte human leukocyte antigen-dr expression in patients with severe sepsis and septic shock.
34290706 HLA-DR (HLA-DR) septic shock NA NA NA lack_of_evidence
besides, we assessed hla-dr membrane expression and lps-induced tnfa production in monocytes through classical flow cytometry assays.resultsconsistent with the flow cytometry results, the total number of tnfa molecules secreted by encapsulated single monocytes was significantly decreased in septic shock patients compared to healthy donors.
12560226 HLA-E (HLA-E) htlv-1-associated myelopathy NA NA NA unclassified
in the present study we demonstrate that cd3+ t cells that bind tetramers of hla-e and express its ligand, the nk-cell inhibitory receptor cd94/nkg2a, were significantly decreased in frequency in patients with human t-cell lymphotropic virus 1 (htlv-1)-associated myelopathy/tropical spastic paraparesis (ham/tsp) but not in asymptomatic htlv-1 carriers.
12560226 HLA-E (HLA-E) spastic paraparesis NA NA NA unclassified
in the present study we demonstrate that cd3+ t cells that bind tetramers of hla-e and express its ligand, the nk-cell inhibitory receptor cd94/nkg2a, were significantly decreased in frequency in patients with human t-cell lymphotropic virus 1 (htlv-1)-associated myelopathy/tropical spastic paraparesis (ham/tsp) but not in asymptomatic htlv-1 carriers.
18190256 HLA-DRB1*01 htlv-1-associated myelopathy NA NA NA unclassified
hla-drb1*0101 is associated with susceptibility to human t lymphotropic virus type 1 (htlv-1)-associated myelopathy/tropical spastic paraparesis (ham/tsp).
18190256 HLA-DRB1*01 spastic paraparesis NA NA NA unclassified
hla-drb1*0101 is associated with susceptibility to human t lymphotropic virus type 1 (htlv-1)-associated myelopathy/tropical spastic paraparesis (ham/tsp).
26848682 HUMAN LEUKOCYTE ANTIGEN (HUMAN LEUKOCYTE ANTIGEN) htlv-1-associated myelopathy NA hepatitis NA only_studied
this review describes the main factors involved in the virus-host balance, especially for some particular human leukocyte antigen (hla) haplotypes, and other important genetic markers in the development of htlv-1-associated myelopathy/tropical spastic paraparesis (ham/tsp) and other persistent viruses, such as hiv and hcv.
26848682 HUMAN LEUKOCYTE ANTIGEN (HUMAN LEUKOCYTE ANTIGEN) spastic paraparesis NA hepatitis NA only_studied
this review describes the main factors involved in the virus-host balance, especially for some particular human leukocyte antigen (hla) haplotypes, and other important genetic markers in the development of htlv-1-associated myelopathy/tropical spastic paraparesis (ham/tsp) and other persistent viruses, such as hiv and hcv.
8937542 HUMAN LEUKOCYTE ANTIGEN (HUMAN LEUKOCYTE ANTIGEN) spastic paraparesis NA NA NA unclassified
in htlv-1 associated myelopathy/tropical spastic paraparesis (ham/tsp), we correlated human leukocyte antigen (hla) haplotypes to the fine specificities of intrathecally synthesized igg antibodies against htlv-1.
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