PMID | Allele | Disease | Population | Drug Names | SNP | Class | Sentence |
---|---|---|---|---|---|---|---|
33813808 | HLA-DR (HLA-DR) | septic shock | NA | polymyxin | NA | unclassified | |
pmx-dhp improved monocyte human leukocyte antigen-dr expression in patients with severe sepsis and septic shock. | |||||||
33813808 | HLA-DR (HLA-DR) | severe sepsis | NA | polymyxin | NA | unclassified | |
pmx-dhp improved monocyte human leukocyte antigen-dr expression in patients with severe sepsis and septic shock. | |||||||
34290706 | HLA-DR (HLA-DR) | septic shock | NA | NA | NA | lack_of_evidence | |
besides, we assessed hla-dr membrane expression and lps-induced tnfa production in monocytes through classical flow cytometry assays.resultsconsistent with the flow cytometry results, the total number of tnfa molecules secreted by encapsulated single monocytes was significantly decreased in septic shock patients compared to healthy donors. | |||||||
12560226 | HLA-E (HLA-E) | htlv-1-associated myelopathy | NA | NA | NA | unclassified | |
in the present study we demonstrate that cd3+ t cells that bind tetramers of hla-e and express its ligand, the nk-cell inhibitory receptor cd94/nkg2a, were significantly decreased in frequency in patients with human t-cell lymphotropic virus 1 (htlv-1)-associated myelopathy/tropical spastic paraparesis (ham/tsp) but not in asymptomatic htlv-1 carriers. | |||||||
12560226 | HLA-E (HLA-E) | spastic paraparesis | NA | NA | NA | unclassified | |
in the present study we demonstrate that cd3+ t cells that bind tetramers of hla-e and express its ligand, the nk-cell inhibitory receptor cd94/nkg2a, were significantly decreased in frequency in patients with human t-cell lymphotropic virus 1 (htlv-1)-associated myelopathy/tropical spastic paraparesis (ham/tsp) but not in asymptomatic htlv-1 carriers. | |||||||
18190256 | HLA-DRB1*01 | htlv-1-associated myelopathy | NA | NA | NA | unclassified | |
hla-drb1*0101 is associated with susceptibility to human t lymphotropic virus type 1 (htlv-1)-associated myelopathy/tropical spastic paraparesis (ham/tsp). | |||||||
18190256 | HLA-DRB1*01 | spastic paraparesis | NA | NA | NA | unclassified | |
hla-drb1*0101 is associated with susceptibility to human t lymphotropic virus type 1 (htlv-1)-associated myelopathy/tropical spastic paraparesis (ham/tsp). | |||||||
26848682 | HUMAN LEUKOCYTE ANTIGEN (HUMAN LEUKOCYTE ANTIGEN) | htlv-1-associated myelopathy | NA | hepatitis | NA | only_studied | |
this review describes the main factors involved in the virus-host balance, especially for some particular human leukocyte antigen (hla) haplotypes, and other important genetic markers in the development of htlv-1-associated myelopathy/tropical spastic paraparesis (ham/tsp) and other persistent viruses, such as hiv and hcv. | |||||||
26848682 | HUMAN LEUKOCYTE ANTIGEN (HUMAN LEUKOCYTE ANTIGEN) | spastic paraparesis | NA | hepatitis | NA | only_studied | |
this review describes the main factors involved in the virus-host balance, especially for some particular human leukocyte antigen (hla) haplotypes, and other important genetic markers in the development of htlv-1-associated myelopathy/tropical spastic paraparesis (ham/tsp) and other persistent viruses, such as hiv and hcv. | |||||||
8937542 | HUMAN LEUKOCYTE ANTIGEN (HUMAN LEUKOCYTE ANTIGEN) | spastic paraparesis | NA | NA | NA | unclassified | |
in htlv-1 associated myelopathy/tropical spastic paraparesis (ham/tsp), we correlated human leukocyte antigen (hla) haplotypes to the fine specificities of intrathecally synthesized igg antibodies against htlv-1. |
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