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| PMID | Allele | Disease | Population | Drug Names | SNP | Class | Sentence |
|---|---|---|---|---|---|---|---|
| 30772931 | HLA-DR (HLA-DR) | postoperative wound infection | NA | NA | NA | unclassified | |
| effects of interventions varied less than expected between studies: for categorical variables, for instance postoperative wound infection, p < 1 x 10-7 , and for continuous variables, for instance hla-dr concentration, p = 0.00001. | |||||||
| 30786885 | HLA-DR (HLA-DR) | infections hiv | NA | NA | NA | positive | |
| additionally, when comparing infected p24+ cells to bystander uninfected p24- cells (after bulk hiv infections), hiv replication significantly increased t cell activation (cd69, cd25, hla.dr, cd38, and ki67) without concomitantly increasing cyct1 protein levels, possibly due to hijacking of p-tefb by the viral tat protein. | |||||||
| 30792213 | HLA (HLA) | primary hemophagocytic lymphohistiocytosis | NA | NA | NA | unclassified | |
| finally, we obtained successful donor engraftment in 2 out of 3 children with primary hemophagocytic lymphohistiocytosis who, after experiencing gf, were re-transplanted from the same hla-haploidentical donor under the compassionate use coverage of emapalumab, an anti-ifng monoclonal antibody recently approved by the us food and drug administration for treatment of patients with primary hemophagocytic lymphohistiocytosis. | |||||||
| 30888587 | HLA (HLA) | leishmania infection | NA | NA | NA | unclassified | |
| asymptomatic leishmania infection might be associated with certain hla antigens. | |||||||
| 30905855 | HLA-DR (HLA-DR) | anastomotic leak | NA | NA | NA | unclassified | |
| monocytic hla-dr expression for prediction of anastomotic leak after colorectal surgery. | |||||||
| 30905855 | HLA-DR (HLA-DR) | anastomotic leakage | NA | NA | NA | unclassified | |
| earlier detection of anastomotic leakage (al) after colorectal procedures could minimize the detrimental clinical impact of al and thereby reduce morbidity and mortality.study designwe conducted a prospective study with assessment of the diagnostic accuracy of monocytic hla-dr (mhla-dr) expression compared with wbcs, c-reactive protein (crp), and procalcitonin (pct) in predicting al in patients undergoing elective colorectal operation with anastomosis. | |||||||
| 31053880 | HLA-DR (HLA-DR) | smoldering myeloma | NA | NA | NA | positive | |
| pd-l1, lag3, and hla-dr are increasingly expressed during smoldering myeloma progression. | |||||||
| 31131681 | HLA-G (HLA-G) | coronary heart diseases | NA | NA | NA | unclassified | |
| the 14 bp ins/del polymorphism in the 3'utr of hla-g may influence the susceptibility for diabetes and coronary heart diseases (chd), thus suggesting a novel candidate gene. | |||||||
| 34584012 | HUMAN LEUKOCYTE ANTIGEN (HUMAN LEUKOCYTE ANTIGEN) | encephaliti | NA | NA | NA | unclassified | |
| this study provides evidence for relevant genetic determinants of antibody-mediated autoimmune encephalitides outside the human leukocyte antigen (hla) region. | |||||||
| 32216088 | HLA-B (HLA-B) | adverse drug events | Hispanic | phenytoin | NA | negation | |
| the role of cytochrome p450 (cyp)2c9 and cyp2c19 genetic variation in risk for phenytoin-induced cutaneous adverse drug events is not well understood independently of the human leukocyte antigen b (hla-b)*15:02 risk allele. | |||||||
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