PMID | Allele | Disease | Population | Drug Names | SNP | Class | Sentence |
---|---|---|---|---|---|---|---|
33359499 | HLA-F (HLA-F) | polyomavirus infection | NA | NA | NA | unclassified | |
upregulation of hla-f expression by bk polyomavirus infection induces immune recognition by kir3ds1-positive natural killer cells. | |||||||
33359499 | HLA-F (HLA-F) | polyomavirus infection | NA | NA | NA | positive | |
using an in vitro cell culture model of human bk polyomavirus infection and kidney biopsy samples from patients with bk polyomavirus-associated nephropathy, we observed significantly increased surface expression of the ligand for kir3ds1, hla-f, on bk polyomavirus-infected kidney tubular cells. | |||||||
33359499 | HLA-F (HLA-F) | polyomavirus infection | NA | NA | NA | unclassified | |
thus, our data provide a mechanism by which kir3ds-positive natural killer cells can control bk polyomavirus infection of the kidney, and rationale for exploring hla-f/kir3ds1 interactions for immunotherapeutic approaches in bk polyomavirus-associated nephropathy. | |||||||
28575582 | HLA (HLA) | venezuelan equine encephalitis | Venezuelan | NA | NA | unclassified | |
an immunoinformatics-derived dna vaccine encoding human class ii t cell epitopes of ebola virus, sudan virus, and venezuelan equine encephalitis virus is immunogenic in hla transgenic mice. | |||||||
28575582 | HUMAN LEUKOCYTE ANTIGEN (HUMAN LEUKOCYTE ANTIGEN) | venezuelan equine encephalitis | Venezuelan | NA | NA | unclassified | |
immunoinformatics tools were used to predict human leukocyte antigen (hla) class ii-restricted t cell epitopes within the envelope glycoproteins and nucleocapsid proteins of ebola virus (ebov) and sudan virus (sudv) and the structural proteins of venezuelan equine encephalitis virus (veev). | |||||||
29786170 | HLA-A*02 | triple negative breast cancer | NA | NA | NA | unclassified | |
immunopeptidomic profiling of hla-a2-positive triple negative breast cancer identifies potential immunotherapy target antigens. | |||||||
29786170 | HLA-A*02 | triple negative breast cancer | NA | NA | NA | unclassified | |
here we analyzed the immunopeptidomes of six hla-a2-positive triple negative breast cancer (tnbc) samples by nano-ultra performance liquid chromatography tandem mass spectrometry (nuplc-ms2 ). | |||||||
34589428 | HLA-B (HLA-B) | triple negative breast cancer | NA | NA | NA | unclassified | |
b4galnt2 gene promotes proliferation, and invasiveness and migration abilities of model triple negative breast cancer (tnbc) cells by interacting with hla-b protein. | |||||||
28965938 | HLA-B*27 | hidrosadenitis | NA | NA | NA | unclassified | |
in the hidrosadenitis suppurativa group, only hla b27 was found to be associated with a diagnosis of spondyloarthritis. | |||||||
28976134 | HLA (HLA) | bone cancers | NA | NA | NA | unclassified | |
mapping of tp 53 mutations in bone cancers present in cosmic database to its secondary and tertiary structure with in silico prediction of newly formed hla binding epitopes as candidates for synthetic peptide vaccine. |
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