Copyright 2024
| PMID | Allele | Disease | Population | Drug Names | SNP | Class | Sentence |
|---|---|---|---|---|---|---|---|
| 26025434 | HLA-B*51 | melena | NA | NA | NA | positive | |
| the existence of either hla-b51, melena, or elevated crp of more than 4 mg/dl predicted the refractory form of bd with 100% sensitivity and 85.7% specificity. | |||||||
| 26181685 | HLA-B (HLA-B) | cryptococcal meningitis | NA | NA | NA | negative | |
| overexpression of major histocompatibility complexes, class i, b (hla-b), actin alpha 2 smooth muscle aorta (acta2) and caveolin 1 (cav1) and downregulation of peripheral myelin protein 2 (pmp2) and alpha crystallin b chain (cryab) in cryptococcal meningitis were confirmed by ihc-based validation experiments. | |||||||
| 26185130 | HUMAN LEUKOCYTE ANTIGEN (HUMAN LEUKOCYTE ANTIGEN) | tumor plasma cells | NA | NA | NA | negative | |
| however, by interacting directly with cd28 on live (nonapoptotic) tumor plasma cells, bone marrow mdcs downregulate the expression of proteasome subunits in these cells, thus enabling their evasion from human leukocyte antigen (hla) class i-restricted cd8(+) t-cell killing. | |||||||
| 26231221 | MHC (MHC) | whooping cough | NA | NA | rs9271768 | only_studied | |
| genome-wide association study identifies snps in the mhc class ii loci that are associated with self-reported history of whooping cough. | |||||||
| 26231221 | MHC (MHC) | whooping cough | NA | NA | rs9271768 | unclassified | |
| genetic variation at the mhc class ii region plays a role in susceptibility to whooping cough. | |||||||
| 34011534 | HLA (HLA) | hypophysitis | NA | NA | NA | negation | |
| in this case-control study, apas and hla alleles were analyzed in 62 patients (17 who developed ici-induced isolated adrenocorticotropic hormone deficiency (ici-iad), 5 who developed ici-induced hypophysitis (ici-h) and 40 who did not develop pituitary iraes) treated with icis between november 2, 2015, and march 31, 2020, at nagoya university hospital. | |||||||
| 26473621 | HLA (HLA) | channelopathies | American | NA | rs55687265 | unclassified | |
| genes involved in e3 ubiquitin-protein ligase complex (asb10) and cyclic nucleotide gated channelopathies (cngb3) as well as hla-drb5 and hspb2 (heat-shock protein 27) provided additional evidence of association (p < 10(-5)). | |||||||
| 26483904 | HLA (HLA) | catalepsy | NA | NA | NA | unclassified | |
| these sisters are two of the few cases in the literature concordant for narcolepsy with catalepsy and without a "positive hla" for narcolepsy. | |||||||
| 26567026 | HUMAN LEUKOCYTE ANTIGEN (HUMAN LEUKOCYTE ANTIGEN) | fuchs endothelial dystrophy | NA | NA | NA | unclassified | |
| the analysis was stratified for primary corneal diagnosis (fuchs endothelial dystrophy (fed), pseudophakic bullous keratopathy (pbk) and other) and corrected for potentially confounding factors (human leukocyte antigen matching, donor trephine diameter, deep vascularisation, the occurrence of reversible rejection episodes and receipt of systemic antiviral medication, long-term steroids or other immunosuppressive agents). | |||||||
| 26748574 | HLA MATCHED (HLA-MATCHED) | emberger syndrome | NA | NA | NA | unclassified | |
| the patient was diagnosed with emberger syndrome by sequencing of gata2 dna, and underwent rist from an hla-matched unrelated donor. | |||||||
Copyright 2024