PMID | Allele | Disease | Population | Drug Names | SNP | Class | Sentence |
---|---|---|---|---|---|---|---|
18835950 | HLA (HLA) | diabetes complications | Finnish | insulin | NA | negation | |
in contrast, no association was observed with blood pressure, diabetes complications, or hla genotype distribution. | |||||||
18842336 | HLA-DR (HLA-DR) | pagets disease of the breast | NA | NA | NA | only_studied | |
paraffin-embedded samples of paget's disease of the breast (n=27) and of disease-free epidermis of the nipple (n=10) were investigated immunohistochemically for the presence of dendritic cells, in particular of langerhans cells, using antibodies against s-100, cd1a, and hla-dr, as well as novel reagents against langerin/cd207, dc-lamp/cd208 and p55 (fascin), the latter two being specific for mature dendritic cells. | |||||||
19020464 | DQ8 (HAPLOTYPE) | celiac diseases | NA | NA | NA | unclassified | |
genetic testing before screening would potentially reduce costs by eliminating hla-dq2 and dq8 negative patients who are at extremely low risk for developing celiac disease.studya decision tree was developed incorporating 3 diagnostic branches: initial screening with anti-tissue transglutaminase at time t0, repeat screening at time t1, and genetic testing before repeat screening. | |||||||
19020464 | DQ2 (HAPLOTYPE) | celiac diseases | NA | NA | NA | unclassified | |
genetic testing before screening would potentially reduce costs by eliminating hla-dq2 and dq8 negative patients who are at extremely low risk for developing celiac disease.studya decision tree was developed incorporating 3 diagnostic branches: initial screening with anti-tissue transglutaminase at time t0, repeat screening at time t1, and genetic testing before repeat screening. | |||||||
31041208 | HLA (HLA) | celiac diseases | NA | NA | NA | unclassified | |
contextin the resource poor country like india it is difficult to get hla screening and ema testing in patients with celiac disease in small centres.aimsto study the effect of gluten free diet on iga tissue transglutaminase levels and various growth parameters in patients with celiac disease.settings and designthis was a prospective study conducted in the department of paediatrics of a tertiary referral hospital in north india in 3 stages viz. | |||||||
32790217 | NA (NA) | disease genetic | European | NA | NA | negation | |
human leukocyte antigen (hla) dq gene testing is available in clinic but does not include non-hla attributed risk and is limited by discrete risk stratification.aimsto accurately characterise both hla and non-hla coeliac disease genetic risk as a single nucleotide polymorphism-based grs and evaluate diagnostic utility. | |||||||
32790217 | NA (NA) | disease genetic | European | NA | NA | negation | |
human leukocyte antigen (hla) dq gene testing is available in clinic but does not include non-hla attributed risk and is limited by discrete risk stratification.aimsto accurately characterise both hla and non-hla coeliac disease genetic risk as a single nucleotide polymorphism-based grs and evaluate diagnostic utility. | |||||||
32790217 | NA (NA) | disease genetic | European | NA | NA | unclassified | |
a single nucleotide polymorphism-based grs may offer more effective and cost-efficient testing of coeliac disease genetic risk in comparison to hla-dq stratification. | |||||||
19077909 | HLA-DR (HLA-DR) | neuroendocrine carcinomas | NA | NA | NA | unclassified | |
a limited immunohistochemical panel of ck, ck5/6, p63, and hla-dr is useful in discriminating nasopharyngeal, basaloid squamous cell, and high-grade neuroendocrine carcinomas of the sinonasal cavity and nasopharynx. | |||||||
19091577 | HLA-DR (HLA-DR) | senile plaques | NA | NA | NA | positive | |
microglial cells adjacent to senile plaques were positive for hla-dr expression, and astroglial cells positive for glial fibrillary acidic protein were scattered around the microglial cells. |
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