Copyright 2024
| PMID | Allele | Disease | Population | Drug Names | SNP | Class | Sentence |
|---|---|---|---|---|---|---|---|
| 17929129 | HLA-B*27 | amyloid deposit | NA | NA | NA | unclassified | |
| we used transgenic rats with hla-b27 and beta 2-m to develop an in vivo animal model with beta 2-m amyloid-associated disorders to investigate the mechanism of formation and to report histological findings of beta 2-m amyloid deposition. | |||||||
| 32363949 | HUMAN LEUKOCYTE ANTIGEN (HUMAN LEUKOCYTE ANTIGEN) | dyslipidemia | European | NA | NA | only_studied | |
| among candidate predictors assessed, 6 early independent predictors of these trajectories were identified: donor age (p<0.001), donor male sex (p<0.001), donor tobacco consumption (p=0.001), recipient dyslipidemia (p=0.009), class ii anti-human leukocyte antigen donor-specific antibodies (p=0.004), and acute cellular rejection >=2r (p=0.028). | |||||||
| 33417479 | HLA (HLA) | dyslipidemia | NA | NA | NA | unclassified | |
| older (>= 50 years) age (hazard ratio [hr], 2.76; 95% ci, 1.37 to 5.58), hla-unrelated donor (hr, 2.20; 95% ci, 1.18 to 4.12), dyslipidemia (hr, 2.40; 95% ci, 1.23 to 4.68), and pre-hct prolonged qtc interval (hr, 2.55; 95% ci, 1.38 to 4.72) were independent risk factors for af. | |||||||
| 17972826 | HLA-DR (HLA-DR) | mantle zone lymphoma | NA | NA | NA | unclassified | |
| immunophenotype studies of mononuclear cells of the peripheral blood showed characteristic membranous phenotype for mantle zone lymphoma in leukaemic phase: smlg+ (lambda light chain) | |||||||
| 17986665 | HLA-DRB1*07 | large granular lymphocytosis | NA | NA | NA | unclassified | |
| in addition, these tcr sequences are highly homologous to those observed in hla-dr7(+) patients with cd4(+) t-cell large granular lymphocytosis and implicate cytomegalovirus as a likely antigenic stimulus for this disorder. | |||||||
| 32241232 | HLA-B*27 | diffuse idiopathic skeletal hyperostosis | NA | NA | NA | positive | |
| the radiographs revealed multilevel changes consistent with diffuse idiopathic skeletal hyperostosis, and the hla-b27 test was positive. | |||||||
| 27878749 | HLA (HLA) | staphylococcal pneumonia | NA | NA | NA | unclassified | |
| we reported the inhibition of a-hemolysin (hla) production in methicillin-resistant staphylococcus aureus usa300 by osthole and further investigated the combination of osthole and baicalin in the treatment of staphylococcal pneumonia. | |||||||
| 18312330 | HLA (HLA) | tinea | NA | NA | NA | positive | |
| we assessed the levels of the various lymphocyte subsets, the hla haplotypes, the expression of various receptors on natural killer (nk) cells and the serum levels of cytokines, in a family in which four siblings had tinea corporis, while four others were healthy, in order to reveal potential factors of susceptibility to dermatophytes.observationsnormal numbers of t, b and nk cells were found in the peripheral blood, without significant differences between healthy and infected siblings. | |||||||
| 18496418 | HLA-DQB1*05 | gonorrhea | NA | NA | NA | unclassified | |
| in addition, 2 human leukocyte antigen variants (cw*04 and dqb1*05) were also independently associated with gonorrhea (adjusted relative odds = 1.9 and 0.5, respectively; p <0.05 for both). | |||||||
| 30919146 | HLA-B*27 | gonorrhea | NA | NA | NA | unclassified | |
| common investigations in rea included inflammatory markers, hla-b27, chlamydia and gonorrhea testing, stool cultures, synovial fluid analyses, si joint imaging. | |||||||
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