PMID | Allele | Disease | Population | Drug Names | SNP | Class | Sentence |
---|---|---|---|---|---|---|---|
25662305 | HLA (HLA) | drug allergy | NA | penicillin | NA | unclassified | |
advances in drug allergy include identification of hla associations for penicillin allergy and a microrna biomarker/mechanism for toxic epidermal necrolysis. | |||||||
25662305 | HLA (HLA) | toxic epidermal necrolysis | NA | penicillin | NA | unclassified | |
advances in drug allergy include identification of hla associations for penicillin allergy and a microrna biomarker/mechanism for toxic epidermal necrolysis. | |||||||
26654817 | HLA (HLA) | drug allergy | NA | NA | NA | unclassified | |
the risk of drug allergy and of a complicated clinical course depends on the individual degree of immune activation, the dose, duration of treatment, route of administration, patient sex as well as hla-traits, which are increasingly being identified. | |||||||
31696802 | HUMAN LEUKOCYTE ANTIGEN (HUMAN LEUKOCYTE ANTIGEN) | drug allergy | NA | NA | NA | unclassified | |
some of the currently available biomarkers are few genetic associations of drug allergy with polymorphisms of human leukocyte antigen (hla), the detection of inflammatory and lipid mediators in serum, or the detection of cytokines, chemokines, and cytotoxic markers in skin biopsies. | |||||||
31677529 | HLA-DR (HLA-DR) | pleural tuberculosis | NA | NA | NA | unclassified | |
in pleural tuberculosis (tb) patients, high expression of btla and b7-h4 promoted a high level of cd83 and hla-dr, which had a negative regulatory effect on mdcs on anti-tb immunity. | |||||||
11604365 | HLA (HLA) | haploidentical transplantations | NA | NA | NA | unclassified | |
the different possible sources of hscs (bone marrow, blood, and cord blood) and better knowledge of hla typing has led to the development of new transplantation techniques and modalities (transplantations after non-myeloablative conditioning, haploidentical transplantations, etc. | |||||||
18086494 | HLA IDENTICAL (HLA-IDENTICAL) | haploidentical transplantations | NA | NA | NA | negation | |
t cell-depleted haploidentical transplantations are successful if there is no hla-identical donor. | |||||||
18545236 | HLA (HLA) | haploidentical transplantations | European | NA | NA | unclassified | |
conditioning regimens are being modified with data accumulating on the role of, for example, pre-transplant residual disease, advanced hla-typing or haploidentical transplantations in the pediatric setting. | |||||||
30708190 | HLA (HLA) | haploidentical transplantations | NA | NA | NA | unclassified | |
haploidentical transplantations have achieved comparable survival as hla fully matched unrelated donors (urds). | |||||||
30708190 | HLA (HLA) | haploidentical transplantations | NA | NA | NA | unclassified | |
when choosing the best donor for hla haploidentical transplantations, most institutions prioritize using young male donors over mother donors. |
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