Copyright 2024
| PMID | Allele | Disease | Population | Drug Names | SNP | Class | Sentence |
|---|---|---|---|---|---|---|---|
| 18821667 | HLA (HLA) | idiopathic inflammatory myopathy | Caucasian | NA | rs2476601 | unclassified | |
| the protein tyrosine phosphatase n22 gene is associated with juvenile and adult idiopathic inflammatory myopathy independent of the hla 8.1 haplotype in british caucasian patients. | |||||||
| 22186711 | HLA-DRB1*03 | idiopathic inflammatory myopathies | Hungarian | NA | NA | unclassified | |
| interaction of hla-drb1*03 and smoking for the development of anti-jo-1 antibodies in adult idiopathic inflammatory myopathies: a european-wide case study. | |||||||
| 22186711 | HLA-DRB1*03 | idiopathic inflammatory myopathies | Hungarian | NA | NA | positive | |
| shla-drb1*03 is strongly associated with anti-jo-1-positive idiopathic inflammatory myopathies (iim) and there is now increasing evidence that jo-1 antigen is preferentially expressed in lung tissue. | |||||||
| 26362759 | HLA (HLA) | idiopathic inflammatory myopathies | Caucasian | NA | NA | unclassified | |
| dense genotyping of immune-related loci in idiopathic inflammatory myopathies confirms hla alleles as the strongest genetic risk factor and suggests different genetic background for major clinical subgroups. | |||||||
| 30146738 | HUMAN LEUKOCYTE ANTIGEN (HUMAN LEUKOCYTE ANTIGEN) | idiopathic inflammatory myopathies | Chinese | NA | NA | only_studied | |
| sprevious association studies have identified genetic variants in the human leukocyte antigen (hla) complex as substantial risk factors for idiopathic inflammatory myopathies (iims). | |||||||
| 10902606 | HLA (HLA) | disease genetics | NA | NA | NA | unclassified | |
| in addition, an overview on hla microsatellite analysis application is presented, with a special focus on disease genetics studies in the form of recent references where the use of microsatellites of the hla region was a key tool. | |||||||
| 12694579 | HLA (HLA) | disease genetics | NA | NA | NA | unclassified | |
| we discuss the current state of play in coeliac disease genetics, focussing particularly on the hla complex. | |||||||
| 28877428 | MHC (MHC) | disease genetics | NA | NA | NA | positive+negation | |
| we suggest that despite already showing the highest number of disease associations, the true extent of the involvement of the mhc region in disease genetics may not have been uncovered. | |||||||
| 10902751 | HLA (HLA) | juvenile idiopathic arthritis | NA | NA | NA | unclassified | |
| to use statistical techniques to identify underlying subtypes of juvenile idiopathic arthritis (jia) that best explain the observed relationships of clinical and laboratory variables, and to compare the statistically derived subtypes with those defined by the international league of associations for rheumatology (ilar) criteria and examine them for hla associations. | |||||||
| 11874841 | HLA-DQB1*04 | juvenile idiopathic arthritis | Polish | NA | NA | negation | |
| juvenile idiopathic arthritis (jia) is primarily associated with hla-dr8 but not dq4 on the dr8-dq4 haplotype. | |||||||
Copyright 2024