PMID | Allele | Disease | Population | Drug Names | SNP | Class | Sentence |
---|---|---|---|---|---|---|---|
30003355 | HUMAN LEUKOCYTE ANTIGEN (HUMAN LEUKOCYTE ANTIGEN) | age-related macular degeneration | Japanese | NA | NA | unclassified | |
we are currently exploring treating hla matched patients of age-related macular degeneration (amd) by using allogenic retinal pigment epithelium cells derived from induced pluripotent stem cells (ips-rpe) from human leukocyte antigen (hla) homozygote donors. | |||||||
30547672 | HLA-DRB1*04 | typhoid | NA | NA | NA | unclassified | |
they also bind to the typhoid-resistant human leukocyte antigen (hla) alleles drb1*0401. | |||||||
30547672 | HUMAN LEUKOCYTE ANTIGEN (HUMAN LEUKOCYTE ANTIGEN) | typhoid | NA | NA | NA | unclassified | |
they also bind to the typhoid-resistant human leukocyte antigen (hla) alleles drb1*0401. | |||||||
30886613 | HLA-E (HLA-E) | typhoid | NA | NA | NA | unclassified | |
s. typhi challenge studies have shown that baseline, multifunctional hla-e responsive t cells are associated with protection from, and delayed onset of, typhoid disease. | |||||||
30886613 | HLA-E (HLA-E) | typhoid fever | NA | NA | NA | unclassified | |
however, despite the overwhelming burden of typhoid fever in school-aged children, and due to limited availability of pediatric samples, incomplete information is available regarding these important hla-e-restricted responses in children, even though studies have shown that younger children may be less likely to develop protective cell mediated immune (cmi) responses than adults following vaccination. | |||||||
30915080 | HLA-DR (HLA-DR) | critical illness | NA | NA | NA | unclassified | |
results: depending on the hla-dr threshold applied for stratification (<=8,000/<=5,000/<=2,000 molecules/cell), a large group of patients (85.5/68.2/40.0%) already presented with a robust decrease of hla-dr on admission, independent of the cause for critical illness. | |||||||
33324414 | HLA-DR (HLA-DR) | critical illness | NA | NA | NA | only_studied | |
we also identified the percentage of hla-dr+cd4+ t cells, pd-1+cd+4/cd8+ t cells in blood, and the neutrophil/lymphocyte ratio as useful factors for predicting critical illness and fatal outcome in patients with confirmed covid-19. | |||||||
10706301 | HLA-DR (HLA-DR) | gastroesophageal reflux disease | NA | NA | NA | only_studied | |
and immunologic analysis (interleukin [il]-6, il-10, leukocytes, hla-dr monocytes) was carried out on the peripheral blood of 34 patients who underwent elective nissen fundoplication by the laparoscopic (lap; n = 26) or conventional (open; n = 8) technique for gastroesophageal reflux disease. | |||||||
28079238 | HUMAN LEUKOCYTE ANTIGEN (HUMAN LEUKOCYTE ANTIGEN) | gastroesophageal reflux disease | Iraqi | NA | NA | unclassified | |
human leukocyte antigen hladrb1 determinants susceptibility to gastroesophageal reflux disease. | |||||||
11676161 | HLA-B*51 | aphthous ulcers | NA | NA | NA | unclassified | |
the diagnosis of neuro-behcet's disease was made by the past history of recurrent genital and aphthous ulcers and positive hla-b51. |
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