Copyright 2024
| PMID | Allele | Disease | Population | Drug Names | SNP | Class | Sentence |
|---|---|---|---|---|---|---|---|
| 12384931 | HLA (HLA) | juvenile idiopathic arthritis | Caucasian | NA | NA | negation | |
| although multiple associations between hla loci and juvenile oligoarthritis have previously been documented, evidence for linkage of hla loci in oligoarthritis in uk caucasians with juvenile idiopathic arthritis (jia) has not been described. | |||||||
| 12847547 | HLA-DRB1 (HLA-DRB1) | juvenile idiopathic arthritis | Finnish | NA | NA | unclassified | |
| analysis of mhc region genetics in finnish patients with juvenile idiopathic arthritis: evidence for different locus-specific effects in polyarticular vs pauciarticular subsets and a shared drb1 epitope. | |||||||
| 15343265 | HLA-DPB1 (HLA-DPB1) | juvenile idiopathic arthritis | Finnish | NA | NA | unclassified | |
| hla-drb1, tap2/tap1, and hla-dpb1 haplotypes in finnish juvenile idiopathic arthritis: more complexity within the mhc. | |||||||
| 15343265 | HLA-DRB1 (HLA-DRB1) | juvenile idiopathic arthritis | Finnish | NA | NA | unclassified | |
| hla-drb1, tap2/tap1, and hla-dpb1 haplotypes in finnish juvenile idiopathic arthritis: more complexity within the mhc. | |||||||
| 15494352 | HLA-B*27 | juvenile idiopathic arthritis | NA | NA | NA | unclassified | |
| none were considered to have a specific subtype of juvenile idiopathic arthritis (jia) and all tested were negative for hla-b27. | |||||||
| 15993233 | MHC (MHC) | juvenile idiopathic arthritis | NA | NA | NA | negation | |
| we undertook in-vitro mhc binding studies with the identified peptides, and hla class ii typing of a subset of patients with juvenile idiopathic arthritis.findingsfive of the eight peptides identified yielded proliferative t-cell responses in 50-70% of pbmc from patients with juvenile idiopathic arthritis irrespective of mhc genotype, but not in pbmc from healthy or disease controls. | |||||||
| 15993233 | HLA-CLASS II (HLA CLASS II) | juvenile idiopathic arthritis | NA | NA | NA | negation | |
| we undertook in-vitro mhc binding studies with the identified peptides, and hla class ii typing of a subset of patients with juvenile idiopathic arthritis.findingsfive of the eight peptides identified yielded proliferative t-cell responses in 50-70% of pbmc from patients with juvenile idiopathic arthritis irrespective of mhc genotype, but not in pbmc from healthy or disease controls. | |||||||
| 15993233 | MHC (MHC) | juvenile idiopathic arthritis | NA | NA | NA | only_studied | |
| in patients with oligoarticular disease, the immune responses to the hsp60 epitopes identified could contribute to disease remission.relevance to practicethe broad recognition of these hsp60 epitopes in a population of patients with polymorphic mhc genotypes opens the way for hsp60-peptide immunotherapy, representing a novel treatment option to specifically modulate the immune system in patients with juvenile idiopathic arthritis. | |||||||
| 18227193 | HLA-B*27 | juvenile idiopathic arthritis | Norwegian | NA | NA | unclassified | |
| autoantibodies and the presence of hla-b27 were associated with juvenile idiopathic arthritis. | |||||||
| 19210888 | HLA-DRB1 (HLA-DRB1) | juvenile idiopathic arthritis | Hungarian | NA | rs2476601 | unclassified | |
| role of hla-drb1 and ptpn22 genes in susceptibility to juvenile idiopathic arthritis in hungarian patients. | |||||||
Copyright 2024