PMID | Allele | Disease | Population | Drug Names | SNP | Class | Sentence |
---|---|---|---|---|---|---|---|
11845225 | NA (NA) | autoimmune diabetes | NA | insulin | NA | unclassified | |
given the fact that in humans the highest risk-conferring locus associated and linked to the disease is the hla cluster, and that hla-dq molecules play a key role in the development of autoimmune diabetes, our observations imply that as yet unidentified immunologic abnormalities could well exist in seronegative relatives at risk of developing clinical diabetes and carrying 2 hla-dq high-risk haplotypes. | |||||||
12173302 | HUMAN LEUKOCYTE ANTIGEN (HUMAN LEUKOCYTE ANTIGEN) | autoimmune diabetes | Japanese | hepatitis | NA | unclassified | |
she had three susceptible human leukocyte antigen (hla) loci for type 1 autoimmune diabetes. | |||||||
12396995 | NA (NA) | autoimmune diabetes | NA | NA | NA | unclassified | |
hla-dq genotypes in classic type 1 diabetes and in latent autoimmune diabetes of the adult. | |||||||
12396995 | NA (NA) | autoimmune diabetes | NA | NA | NA | unclassified | |
the aims of this study were to clarify the importance of age at diagnosis of diabetes for hla-dq associations in patients with classic type 1 diabetes and whether patients considered to have latent autoimmune diabetes of the adult differed in their human leukocyte antigen (hla) associations. | |||||||
12396995 | NA (NA) | autoimmune diabetes | NA | NA | NA | negation | |
the authors conclude that there were no major effects of age at diagnosis on hla-dq associations in classic type 1 diabetic patients, whereas lack of hla-dq protective genotypes was a feature of patients with slow-progressing type 1 diabetes (latent autoimmune diabetes of the adult). | |||||||
12547879 | HLA-DRB1*04 | autoimmune diabetes | NA | NA | NA | positive+negation | |
the prevalence of hla-dqb1*0302, -dr4, -dr3, and -dr3/dr4 risk alleles and the dr4-dqb1*0302 high-risk haplotype did not differ in the two forms of autoimmune diabetes. | |||||||
12547879 | HLA-DQB1*03 | autoimmune diabetes | NA | NA | NA | positive+negation | |
the prevalence of hla-dqb1*0302, -dr4, -dr3, and -dr3/dr4 risk alleles and the dr4-dqb1*0302 high-risk haplotype did not differ in the two forms of autoimmune diabetes. | |||||||
12547879 | HLA-DR3 (BROAD ANTIGEN) | autoimmune diabetes | NA | NA | NA | positive+negation | |
the prevalence of hla-dqb1*0302, -dr4, -dr3, and -dr3/dr4 risk alleles and the dr4-dqb1*0302 high-risk haplotype did not differ in the two forms of autoimmune diabetes. | |||||||
16042135 | HLA-DQB1 (HLA-DQB1) | autoimmune diabetes | NA | insulin | NA | unclassified | |
autoimmune diabetes has strong class ii hla association mainly with dqb gene which constitutes the first susceptibility locus. | |||||||
16042135 | HLA-DQB1 (HLA-DQB1) | latent autoimmune diabetes of adults | NA | insulin | NA | unclassified | |
[hla dqb1 genotyping in latent autoimmune diabetes of adults (lada)]. |
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