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PMID Allele Disease Population Drug Names SNP Class Sentence
30319561 HLA (HLA) endocarditis NA NA NA unclassified
pathogen-related molecular markers significantly associated with a specific source of bacteremia included the presence of sea, undisrupted hlb and isab genes with catheter-related bacteremia; sed, sple, and fib genes with endocarditis; undisrupted hlb with skin and soft tissue infections; and finally, cc5, msra resistance gene and hla gene with osteoarticular source.
30319561 HLA (HLA) soft tissue infections NA NA NA unclassified
pathogen-related molecular markers significantly associated with a specific source of bacteremia included the presence of sea, undisrupted hlb and isab genes with catheter-related bacteremia; sed, sple, and fib genes with endocarditis; undisrupted hlb with skin and soft tissue infections; and finally, cc5, msra resistance gene and hla gene with osteoarticular source.
16514412 HLA-B*51 streptococcal infection Japanese NA NA positive
although the precise etiology is unclear, high prevalence of human leukocyte antigen (hla)-b51 predisposition and predominantly involved t-helper type 1 cells (th1)-type proinflammatory cytokines and extrinsic streptococcal infection suggest a substantial association with an immunogenetic basis and strengthens the hypothesis that il-12, a potent inducer of th-1 immune reaction, is a putative candidate in its pathogenesis.
16514412 HUMAN LEUKOCYTE ANTIGEN (HUMAN LEUKOCYTE ANTIGEN) streptococcal infection Japanese NA NA positive
although the precise etiology is unclear, high prevalence of human leukocyte antigen (hla)-b51 predisposition and predominantly involved t-helper type 1 cells (th1)-type proinflammatory cytokines and extrinsic streptococcal infection suggest a substantial association with an immunogenetic basis and strengthens the hypothesis that il-12, a potent inducer of th-1 immune reaction, is a putative candidate in its pathogenesis.
26483943 HLA-DQB1*06 streptococcal infection NA NA NA unclassified
we report here the case of a child diagnosed with narcolepsy with cataplexy, positivity for the hla-dqb1*0602 and previous history of streptococcal infection.
27431901 HLA-DR (HLA-DR) nosocomial infections NA NA NA unclassified
our group recently demonstrated that a combination of 3 measures of immune cell function (namely neutrophil cd88, monocyte hla-dr and % regulatory t cells) identified a patient population with a 2.4-5-fold greater risk for susceptibility to nosocomial infections.
28856633 HLA-DR (HLA-DR) nosocomial infections NA NA NA positive
low mhla-dr is associated with an increased risk of nosocomial infections and mortality.
8489544 HLA-DRB1*04 relapsing polychondritis Caucasian NA NA unclassified
susceptibility to relapsing polychondritis is associated with hla-dr4.
8489544 HLA-CLASS II (HLA CLASS II) relapsing polychondritis Caucasian NA NA unclassified
to determine the frequency of hla class ii antigens in caucasian central european patients with relapsing polychondritis (rp).
9002018 HLA-DRB1*04 relapsing polychondritis NA NA NA positive
susceptibility to relapsing polychondritis was significantly associated with hla-dr4 (p < 0.001).
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