PMID | Allele | Disease | Population | Drug Names | SNP | Class | Sentence |
---|---|---|---|---|---|---|---|
30319561 | HLA (HLA) | endocarditis | NA | NA | NA | unclassified | |
pathogen-related molecular markers significantly associated with a specific source of bacteremia included the presence of sea, undisrupted hlb and isab genes with catheter-related bacteremia; sed, sple, and fib genes with endocarditis; undisrupted hlb with skin and soft tissue infections; and finally, cc5, msra resistance gene and hla gene with osteoarticular source. | |||||||
30319561 | HLA (HLA) | soft tissue infections | NA | NA | NA | unclassified | |
pathogen-related molecular markers significantly associated with a specific source of bacteremia included the presence of sea, undisrupted hlb and isab genes with catheter-related bacteremia; sed, sple, and fib genes with endocarditis; undisrupted hlb with skin and soft tissue infections; and finally, cc5, msra resistance gene and hla gene with osteoarticular source. | |||||||
16514412 | HLA-B*51 | streptococcal infection | Japanese | NA | NA | positive | |
although the precise etiology is unclear, high prevalence of human leukocyte antigen (hla)-b51 predisposition and predominantly involved t-helper type 1 cells (th1)-type proinflammatory cytokines and extrinsic streptococcal infection suggest a substantial association with an immunogenetic basis and strengthens the hypothesis that il-12, a potent inducer of th-1 immune reaction, is a putative candidate in its pathogenesis. | |||||||
16514412 | HUMAN LEUKOCYTE ANTIGEN (HUMAN LEUKOCYTE ANTIGEN) | streptococcal infection | Japanese | NA | NA | positive | |
although the precise etiology is unclear, high prevalence of human leukocyte antigen (hla)-b51 predisposition and predominantly involved t-helper type 1 cells (th1)-type proinflammatory cytokines and extrinsic streptococcal infection suggest a substantial association with an immunogenetic basis and strengthens the hypothesis that il-12, a potent inducer of th-1 immune reaction, is a putative candidate in its pathogenesis. | |||||||
26483943 | HLA-DQB1*06 | streptococcal infection | NA | NA | NA | unclassified | |
we report here the case of a child diagnosed with narcolepsy with cataplexy, positivity for the hla-dqb1*0602 and previous history of streptococcal infection. | |||||||
27431901 | HLA-DR (HLA-DR) | nosocomial infections | NA | NA | NA | unclassified | |
our group recently demonstrated that a combination of 3 measures of immune cell function (namely neutrophil cd88, monocyte hla-dr and % regulatory t cells) identified a patient population with a 2.4-5-fold greater risk for susceptibility to nosocomial infections. | |||||||
28856633 | HLA-DR (HLA-DR) | nosocomial infections | NA | NA | NA | positive | |
low mhla-dr is associated with an increased risk of nosocomial infections and mortality. | |||||||
8489544 | HLA-DRB1*04 | relapsing polychondritis | Caucasian | NA | NA | unclassified | |
susceptibility to relapsing polychondritis is associated with hla-dr4. | |||||||
8489544 | HLA-CLASS II (HLA CLASS II) | relapsing polychondritis | Caucasian | NA | NA | unclassified | |
to determine the frequency of hla class ii antigens in caucasian central european patients with relapsing polychondritis (rp). | |||||||
9002018 | HLA-DRB1*04 | relapsing polychondritis | NA | NA | NA | positive | |
susceptibility to relapsing polychondritis was significantly associated with hla-dr4 (p < 0.001). |
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