Copyright 2024
| PMID | Allele | Disease | Population | Drug Names | SNP | Class | Sentence |
|---|---|---|---|---|---|---|---|
| 18241227 | HLA-DQB1*05 | bronchiectasis | NA | NA | NA | positive | |
| we found an increase in the prevalence of hla-drb1*01 dqa1*01/dqb1*05 genes in idiopathic bronchiectasis; that is, the hla-dr1, dq5 haplotype (odds ratio 2.19, 95% confidence interval 1.15-4.16, p = 0.0152) compared with control subjects. | |||||||
| 18608925 | HLA-DQB1*05 | bronchiectasis | NA | NA | NA | positive | |
| a role for adaptive immune mechanisms is suggested by the genetic association of hla-dr1, dq5 with increased susceptibility to idiopathic bronchiectasis. | |||||||
| 18608925 | HLA-DRB1*01 | bronchiectasis | NA | NA | NA | positive | |
| a role for adaptive immune mechanisms is suggested by the genetic association of hla-dr1, dq5 with increased susceptibility to idiopathic bronchiectasis. | |||||||
| 22640844 | HLA (HLA) | bronchiectasis | NA | NA | NA | unclassified | |
| this article discusses how allelic variations, gene modifiers, hla associations, and the interplay of developmental, host, and environmental factors all contribute in lesser and greater degrees, depending on the specific disease, toward the development of bronchiectasis in a spectrum of disease processes. | |||||||
| 15186950 | MHC (MHC) | atorvastatin | NA | statins | NA | negative | |
| NA | |||||||
| 24555909 | HLA-DR (HLA-DR) | bacteremia | NA | NA | NA | only_studied | |
| bacteremia, endotoxemia, white blood cells, the peripheral lymphocyte subpopulation, human leukocyte antigen-dr (hla-dr), neutrophil-elastase, interleukin-6 and -1, and c-reactive protein (crp) were investigated. | |||||||
| 24555909 | HLA-DR (HLA-DR) | endotoxemia | NA | NA | NA | only_studied | |
| bacteremia, endotoxemia, white blood cells, the peripheral lymphocyte subpopulation, human leukocyte antigen-dr (hla-dr), neutrophil-elastase, interleukin-6 and -1, and c-reactive protein (crp) were investigated. | |||||||
| 24914221 | HLA-DRB1*04 | bacteremia | NA | NA | NA | only_studied | |
| here, we evaluated the role of the bacterial superantigen staphylococcal enterotoxin a (sea) in a bacteremia model using humanized transgenic mice expressing sag-responsive hla-dr4 molecules. | |||||||
| 25392350 | HLA (HLA) | bacteremia | NA | NA | NA | unclassified | |
| characterization of alpha-toxin hla gene variants, alpha-toxin expression levels, and levels of antibody to alpha-toxin in hemodialysis and postsurgical patients with staphylococcus aureus bacteremia. | |||||||
| 30319561 | HLA (HLA) | bacteremia | NA | NA | NA | unclassified | |
| pathogen-related molecular markers significantly associated with a specific source of bacteremia included the presence of sea, undisrupted hlb and isab genes with catheter-related bacteremia; sed, sple, and fib genes with endocarditis; undisrupted hlb with skin and soft tissue infections; and finally, cc5, msra resistance gene and hla gene with osteoarticular source. | |||||||
Copyright 2024