Copyright 2024
| PMID | Allele | Disease | Population | Drug Names | SNP | Class | Sentence |
|---|---|---|---|---|---|---|---|
| 29151323 | HLA-CLASS I (HLA CLASS II) | brucellosis | NA | NA | NA | unclassified | |
| investigation of human leukocyte antigen in osteoarticular brucellosis background/aim: to determine the relationship between human leukocyte antigen (hla) antigens and osteoarticular brucellosis by evaluating hla class i and ii antigens in control subjects and patients developing osteoarticular brucellosis in turkey.materials and methods: the study included 28 patients with osteoarticular involvement diagnosed with brucellosis and 100 controls. | |||||||
| 29151323 | HUMAN LEUKOCYTE ANTIGEN (HUMAN LEUKOCYTE ANTIGEN) | brucellosis | NA | NA | NA | unclassified | |
| investigation of human leukocyte antigen in osteoarticular brucellosis background/aim: to determine the relationship between human leukocyte antigen (hla) antigens and osteoarticular brucellosis by evaluating hla class i and ii antigens in control subjects and patients developing osteoarticular brucellosis in turkey.materials and methods: the study included 28 patients with osteoarticular involvement diagnosed with brucellosis and 100 controls. | |||||||
| 29151323 | HLA-CLASS I (HLA CLASS II) | brucellosis | NA | NA | NA | unclassified | |
| among the hla class i antigens, hla-cw*10 was determined in 35.71% of the patients and 17% of the controls; the difference was significant (p = 0.039).conclusion: in the development of brucellosis, the frequency of hla-cw*10 among hla class i antigens was observed to be increased, and hla-cw*10 was considered likely to cause predisposition to brucellosis. | |||||||
| 25740878 | HLA-B*13 | molar pregnancies | NA | NA | NA | unclassified | |
| manipulation of egfr signalling might thus offer a promising therapeutic avenue for the treatment of molar pregnancies associated with trophoblast hyperplasia.study funding/competing intereststhis study was supported by the austrian science fund (grant p-25187-b13 to j.p.). | |||||||
| 25740878 | HLA-B*13 | hyperplasias | NA | NA | NA | unclassified | |
| manipulation of egfr signalling might thus offer a promising therapeutic avenue for the treatment of molar pregnancies associated with trophoblast hyperplasia.study funding/competing intereststhis study was supported by the austrian science fund (grant p-25187-b13 to j.p.). | |||||||
| 7763110 | HLA-DRB1*04 | bronchiectasis | NA | methacholine | NA | positive+negation | |
| all five patients with bronchiectasis had the pi mm phenotype, four had hla-dr4, four had kcs and three achieved pc20 fev1; these values were not significantly different (p > 0.05) from those in patients without bronchiectasis. | |||||||
| 9389220 | HLA-DQA1*01 | bronchiectasis | NA | NA | NA | unclassified | |
| the patients with bronchiectasis were characterised by low values of fev1, fvc, fef25-75%, and tlco (p < 0.01), a high prevalence of small airways involvement (29% v 5%, p = 0.019), and a low prevalence of hla dqa1 *0501 allele (14% v 33%, p < 0.05). | |||||||
| 16254274 | HLA-C (HLA-C) | bronchiectasis | NA | NA | NA | unclassified | |
| hla-c and killer cell immunoglobulin-like receptor genes in idiopathic bronchiectasis. | |||||||
| 16254274 | HLA-CLASS I (HLA CLASS II) | bronchiectasis | NA | NA | NA | unclassified | |
| a possible role for natural killer (nk) cells is suggested by the observation that familial bronchiectasis occurs in a rare group of individuals with impaired hla class i expression and consequent nk cell dysfunction. | |||||||
| 16254274 | HLA-C (HLA-C) | bronchiectasis | NA | NA | NA | unclassified | |
| because the hla-c locus and killer cell immunoglobulin-like receptors (kirs) are of key importance for nk cell recognition, we analyzed hla-c/kir combinations by genotyping patients with idiopathic bronchiectasis. | |||||||
Copyright 2024