Copyright 2024
| PMID | Allele | Disease | Population | Drug Names | SNP | Class | Sentence |
|---|---|---|---|---|---|---|---|
| 2261349 | HLA IDENTICAL (HLA-IDENTICAL) | transplantation | NA | NA | NA | positive | |
| patients with severe aplastic anaemia (saa) have a relatively high risk of graft rejection after transplantation of bone marrow from hla-identical siblings compared with patients transplanted for leukaemia. | |||||||
| 2261349 | HLA IDENTICAL (HLA-IDENTICAL) | aplastic anaemia | NA | NA | NA | positive | |
| patients with severe aplastic anaemia (saa) have a relatively high risk of graft rejection after transplantation of bone marrow from hla-identical siblings compared with patients transplanted for leukaemia. | |||||||
| 2261349 | NA (NA) | aplastic anaemia | NA | NA | NA | positive | |
| pretransfused patients with severe aplastic anaemia exhibit high numbers of cytotoxic t lymphocyte precursors probably directed at non-hla antigens. | |||||||
| 2283336 | HLA-B*27 | transplantation | NA | NA | NA | unclassified | |
| in the present study, we have used hla-b27 transgenic mice in a xenogeneic transplantation model. | |||||||
| 2283336 | HLA-B*27 | skin transplantation | NA | NA | NA | positive | |
| the results indicate that both transgenic skin transplantation and intravenous (iv) injection of transgenic spleen cells can reverse specific t-cell low responsiveness against the transgenic hla-b27 antigen into high responsiveness in vivo and in vitro. | |||||||
| 2291990 | HLA IDENTICAL (HLA-IDENTICAL) | transplantation | NA | NA | NA | unclassified | |
| extensive t cell depletion of the donor marrow can eliminate the need for post-transplant immunosuppression and reduce the overall risk of gvhd to 10% or less with either hla-identical or hla-nonidentical transplantation, but this benefit is offset by an increased risk of graft failure. | |||||||
| 2291990 | HLA (HLA) | graft-versus-host disease | NA | NA | NA | positive+negation | |
| current prophylaxis regimens do not provide satisfactory control of graft-versus-host disease (gvhd) in patients transplanted with unmodified marrow from an unrelated donor or from a related donor mismatched for more than one hla antigen. | |||||||
| 2293268 | HLA-DR (HLA-DR) | transplantation | Caucasian | NA | NA | unclassified | |
| linkage imbalance for the b and dr loci (hla) was found in a chilean sample of families where a member had been proposed for transplantation. | |||||||
| 2294403 | HLA-B (HLA-B) | transplantation | NA | NA | NA | unclassified | |
| these include the genes for the three major transplantation antigens, hla-a, hla-b, and hla-c, as well as a number of other genes or pseudogenes of unknown biological significance. | |||||||
| 2294403 | HLA-A (HLA-A) | transplantation | NA | NA | NA | unclassified | |
| these include the genes for the three major transplantation antigens, hla-a, hla-b, and hla-c, as well as a number of other genes or pseudogenes of unknown biological significance. | |||||||
Copyright 2024