Copyright 2024
| PMID | Allele | Disease | Population | Drug Names | SNP | Class | Sentence |
|---|---|---|---|---|---|---|---|
| 15932368 | HLA-B*07 | gastro-oesophageal reflux | Indian | NA | NA | positive | |
| barrett's oesophagus in asians, particularly indians, is strongly positively associated with hla-b7; reinforcing a genetic component to gastro-oesophageal reflux disease. | |||||||
| 15949652 | HLA-B (HLA-B) | chronically ill | NA | NA | NA | positive | |
| the hla-b.15 frequency was significantly increased in a subgroup of patients with age at onset in the early 20s, lower educational achievement, occupational disability, chronically ill, more paranoid type. | |||||||
| 32998048 | HUMAN LEUKOCYTE ANTIGEN (HUMAN LEUKOCYTE ANTIGEN) | latent autoimmune diabetes of adults | Japanese | NA | NA | unclassified | |
| the association of human leukocyte antigen class ii (hla ii) haplotypes with the risk of latent autoimmune diabetes of adults (lada): evidence based on available data. | |||||||
| 16105525 | HLA-DR (HLA-DR) | acidosis | NA | NA | NA | positive | |
| severe (<7.1) mucosal acidosis was associated significantly (p< .05) with postoperative septic complications, an increase in postoperative intestinal permeability, c-reactive protein and l-selectin expression, and a decrease (p< .05) in monocyte human leukocyte antigen-dr expression. | |||||||
| 21924707 | MHC (MHC) | acidosis | NA | NA | NA | unclassified | |
| extracellular acidosis promotes neutrophil transdifferentiation to mhc class ii-expressing cells. | |||||||
| 22154780 | HLA-DR (HLA-DR) | acidosis | NA | amiloride | NA | unclassified | |
| we here report that extracellular acidosis (ph 6.5) selectively stimulates the production and the secretion of il-1b by human monocytes without affecting the production of tnf-a, il-6 and the expression of cd40, cd80, cd86, and hla-dr. stimulation of il-1b production by ph 6.5-treated monocytes was shown to be dependent on caspase-1 activity, and it was also observed using peripheral blood mononuclear cells instead of isolated monocytes. | |||||||
| 16107953 | HLA (HLA) | chronic lyme disease | NA | NA | NA | unclassified | |
| a case-control study to examine hla haplotype associations in patients with posttreatment chronic lyme disease. | |||||||
| 16107953 | HLA-DRB1 (HLA-DRB1) | chronic lyme disease | NA | NA | NA | unclassified | |
| in a comparison of 95 patients with systemic symptoms that persisted after antibiotic treatment for acute lyme disease (posttreatment chronic lyme disease) and 104 control subjects without such symptoms after antibiotic treatment, we sought associations between human leukocyte antigen class ii (drb1 and dqb1) markers and posttreatment chronic lyme disease. | |||||||
| 16107953 | HLA-DQB1 (HLA-DQB1) | chronic lyme disease | NA | NA | NA | unclassified | |
| in a comparison of 95 patients with systemic symptoms that persisted after antibiotic treatment for acute lyme disease (posttreatment chronic lyme disease) and 104 control subjects without such symptoms after antibiotic treatment, we sought associations between human leukocyte antigen class ii (drb1 and dqb1) markers and posttreatment chronic lyme disease. | |||||||
| 16172755 | HLA-CLASS II (HLA CLASS II) | jorge lobos disease | NA | NA | NA | unclassified | |
| considering its epidemiology and the few studies on immunological aspects of this disease, the objective of the present study was to investigate a possible association between hla class ii specificities in 21 jorge lobo's disease patients, by comparing them with healthy individual of the same ethnic group. | |||||||
Copyright 2024