Copyright 2024
| PMID | Allele | Disease | Population | Drug Names | SNP | Class | Sentence |
|---|---|---|---|---|---|---|---|
| 22448298 | HLA-DRB1*01 | chagas disease | NA | NA | NA | unclassified | |
| the drb1*0102, b*1402 and mica*011 alleles were in strong linkage disequilibrium (ld), and the hla-drb1*01-b*14-mica*011 haplotype was associated with resistance against chronic chagas disease. | |||||||
| 22448298 | HLA-DRB1*01 | chagas disease | NA | NA | NA | unclassified | |
| the drb1*0102, b*1402 and mica*011 alleles were in strong linkage disequilibrium (ld), and the hla-drb1*01-b*14-mica*011 haplotype was associated with resistance against chronic chagas disease. | |||||||
| 22448298 | HLA (HLA) | chagas disease | NA | NA | NA | unclassified | |
| this is the first report of hla haplotype association with resistance to chronic chagas disease. | |||||||
| 22448298 | HLA-B*14 | megacolon | NA | NA | NA | unclassified | |
| we analyzed their hla genetic polymorphisms (hla-a, hla-b, mica, micb, drb1 and tnf-alpha promoter region) mainly through sequence based and labtype sso typing test using luminex technology.principal findingsthe frequencies of hla-drb1*01 and hla-b*14:02 were significantly lower in patients suffering from megacolon as well as in those with ecg alteration and/or megacolon compared with a group of patients with indeterminate symptoms. | |||||||
| 22448298 | HLA-A (HLA-A) | megacolon | NA | NA | NA | unclassified | |
| we analyzed their hla genetic polymorphisms (hla-a, hla-b, mica, micb, drb1 and tnf-alpha promoter region) mainly through sequence based and labtype sso typing test using luminex technology.principal findingsthe frequencies of hla-drb1*01 and hla-b*14:02 were significantly lower in patients suffering from megacolon as well as in those with ecg alteration and/or megacolon compared with a group of patients with indeterminate symptoms. | |||||||
| 22448298 | HLA-DRB1*01 | megacolon | NA | NA | NA | unclassified | |
| we analyzed their hla genetic polymorphisms (hla-a, hla-b, mica, micb, drb1 and tnf-alpha promoter region) mainly through sequence based and labtype sso typing test using luminex technology.principal findingsthe frequencies of hla-drb1*01 and hla-b*14:02 were significantly lower in patients suffering from megacolon as well as in those with ecg alteration and/or megacolon compared with a group of patients with indeterminate symptoms. | |||||||
| 22523642 | HLA-B*13 | chagas disease | NA | NA | NA | unclassified | |
| evidence for t cell help in the igg response against tandemly repetitive trypanosoma cruzi b13 protein in chronic chagas disease patients. | |||||||
| 22523642 | HLA-B*13 | chagas disease | NA | NA | NA | unclassified | |
| the tandemly repetitive trypanosoma cruzi b13 protein is an immunodominant antigen among chagas disease patients. | |||||||
| 22523642 | HLA-B*13 | chagas disease | NA | NA | NA | only_studied | |
| we assessed whether the presence of hla class ii molecules able to present b13 epitopes to t cells could affect anti-b13 igg levels in a cognate fashion, in both major clinical forms of chronic chagas disease. | |||||||
| 23376085 | HLA-B*14 | chagas disease | NA | NA | NA | unclassified | |
| 21-hydroxylase gene mutant allele cyp21a2*15 strongly linked to the resistant hla haplotype b*14:02-drb1*01:02 in chronic chagas disease. | |||||||
Copyright 2024