Copyright 2024
| PMID | Allele | Disease | Population | Drug Names | SNP | Class | Sentence |
|---|---|---|---|---|---|---|---|
| 26345971 | HLA (HLA) | osteoporosis | Japanese | NA | NA | unclassified | |
| hla is a complex gene family | |||||||
| 26345971 | HLA-A (HLA-A) | postmenopausal osteoporosis | Japanese | NA | NA | unclassified | |
| prompted by these findings, this study was designed to explore the associations between hla-a gene polymorphisms and postmenopausal osteoporosis in the han chinese population. | |||||||
| 26345971 | HLA-A (HLA-A) | postmenopausal osteoporosis | Japanese | NA | NA | unclassified | |
| the polymerase chain reaction-sequence-based typing method was used for dna genotyping at the hla-a locus in 70 patients with postmenopausal osteoporosis and 73 healthy controls. | |||||||
| 26345971 | HLA-A (HLA-A) | postmenopausal osteoporosis | Japanese | NA | NA | only_studied | |
| we identified 17 hla-a alleles in patients with postmenopausal osteoporosis and 20 hla-a alleles in control subjects. | |||||||
| 26345971 | HLA-A (HLA-A) | postmenopausal osteoporosis | Japanese | NA | NA | positive | |
| furthermore, we found that the frequency of the hla-a* 02:07 allele was significantly higher in patients with postmenopausal osteoporosis than in control subjects (p = 0.023), and the relative risk was 4.065 (95% confidence interval = 1.109-14.893). | |||||||
| 26345971 | HLA-A (HLA-A) | postmenopausal osteoporosis | Japanese | NA | NA | unclassified | |
| our study provides supportive evidence for the contribution of hla-a gene polymorphisms to the susceptibility to postmenopausal osteoporosis and suggests that hla-a* 02:07 is likely an important genetic risk factor for postmenopausal osteoporosis in the han chinese population. | |||||||
| 33061329 | HLA-C (HLA-C) | osteoporosis | NA | NA | NA | unclassified | |
| based on the delncrnas-degs interaction network in male osteoporosis, we obtained several interaction pairs including snhg5-syncrip-hba1-hbb, hcg27-hla-c, linc02009-ccr2, and loc101926887-ifit1-ifit2/ifit3/ifit5. | |||||||
| 11037855 | HLA MATCHED (HLA-MATCHED) | busulfan | NA | fludarabine | NA | unclassified | |
| NA | |||||||
| 26670252 | HLA-DR3 (BROAD ANTIGEN) | wound infection | NA | NA | NA | unclassified | |
| we tested our hypothesis using a novel staphylococcal skin wound infection model in transgenic mice expressing hla-dr3. | |||||||
| 27238459 | HLA (HLA) | wound infection | NA | NA | NA | unclassified | |
| in conclusion, our study indicated that the sea, hla, fib and icaa were most frequent genes encoding virulence factors among mrsa with sccmec type iiia isolated from burn wound infection. | |||||||
Copyright 2024