PMID | Allele | Disease | Population | Drug Names | SNP | Class | Sentence |
---|---|---|---|---|---|---|---|
11423179 | HLA-CLASS I (HLA CLASS II) | sjogren's syndrome | Caucasian | NA | NA | unclassified | |
hla class i and class ii are both associated with the genetic predisposition to primary sjogren syndrome. | |||||||
31272097 | HLA (HLA) | sjogren's syndrome | Tunisian | NA | NA | unclassified | |
association of hla alleles with primary sjogren syndrome in the south tunisian population. | |||||||
31272097 | HLA-DRB1 (HLA-DRB1) | sjogren's syndrome | Tunisian | NA | NA | unclassified | |
in order to investigate human leukocyte antigen (hla) genes predisposing to primary sjogren syndrome (pss), we conducted an association study using hla loci (a, b, and drb1) and 9 polymorphic microsatellite markers spanning the hla region in pss patients as compared to healthy individuals.subjects and forty-four patients fitting the european criteria of pss and 123 healthy controls were analyzed for their hla class i and class ii alleles. | |||||||
19925600 | HLA-B*51 | thrombophlebitis | NA | NA | NA | positive+negation | |
though age over 40 years, thrombophlebitis, hla b51 haplotype and ophthalmological involvement were not found to be significantly associated with ma; these parameters increased the risk for ma. | |||||||
26802570 | HLA-DRB1*04 | diabetic ketoacidosis | NA | NA | NA | negation | |
there were no independent associations with sex, race/ethnicity, diabetic ketoacidosis, hba1c , hla dr3-dq2/dr4-dq8 or autoantibody number. | |||||||
26802570 | DQ8 (HAPLOTYPE) | diabetic ketoacidosis | NA | NA | NA | negation | |
there were no independent associations with sex, race/ethnicity, diabetic ketoacidosis, hba1c , hla dr3-dq2/dr4-dq8 or autoantibody number. | |||||||
26802570 | DR3-DQ2 (HAPLOTYPE) | diabetic ketoacidosis | NA | NA | NA | negation | |
there were no independent associations with sex, race/ethnicity, diabetic ketoacidosis, hba1c , hla dr3-dq2/dr4-dq8 or autoantibody number. | |||||||
30848017 | HUMAN LEUKOCYTE ANTIGEN (HUMAN LEUKOCYTE ANTIGEN) | diabetic ketoacidosis | Chinese | insulin | NA | unclassified | |
independent predictors for poor rbf outcome among the 110 patients in the follow-up cohort were age at onset (odds ratio [or] 0.82; 95% confidence interval [ci] 0.73-0.92; p < 0.001), high-risk human leukocyte antigen (hla) status (or 4.73; ci 1.28-17.52; p = 0.020), female sex (or 3.39; ci 1.03-11.22; p = 0.045), and a history of diabetic ketoacidosis (dka; or 8.71; ci 2.31-32.83; p < 0.001). | |||||||
20679961 | HLA-B*35 | NA | Thai | rs4997052 | rs1140412 | unclassified | |
NA | |||||||
20679961 | HUMAN LEUKOCYTE ANTIGEN (HUMAN LEUKOCYTE ANTIGEN) | NA | Thai | rs4997052 | rs1140412 | unclassified | |
NA |
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