Copyright 2024
| PMID | Allele | Disease | Population | Drug Names | SNP | Class | Sentence |
|---|---|---|---|---|---|---|---|
| 9459509 | HLA-DQA1*01 | neurological disorder | Caucasian American | modafinil | NA | unclassified | |
| narcolepsy is a neurological disorder known to be tightly associated with hla-dqa1*0102 and dqb1*0602. | |||||||
| 33863907 | HLA-DQB1*06 | neurological disorder | NA | NA | NA | unclassified | |
| narcolepsy type 1 (nt1) is a chronic neurological disorder having a strong association with hla-dqb1*0602, thereby suggesting an immunological origin. | |||||||
| 9102877 | HLA (HLA) | febrile nonhemolytic transfusion reactions | NA | NA | NA | unclassified | |
| red cells depleted of white cells can prevent febrile nonhemolytic transfusion reactions and may reduce or delay alloimmunization of hla antigens and the transfusion of various viruses. | |||||||
| 11896329 | HLA (HLA) | febrile nonhemolytic transfusion reactions | NA | NA | NA | unclassified | |
| in adults, wbc reduction has been shown to reduce the frequency of hla alloimmunization, cmv and htlv infections, and febrile nonhemolytic transfusion reactions. | |||||||
| 11896329 | HLA (HLA) | htlv infections | NA | NA | NA | unclassified | |
| in adults, wbc reduction has been shown to reduce the frequency of hla alloimmunization, cmv and htlv infections, and febrile nonhemolytic transfusion reactions. | |||||||
| 12394176 | HLA (HLA) | febrile nonhemolytic transfusion reactions | NA | NA | NA | unclassified | |
| the emerging scientific and clinical evidence reviewed in this article demonstrates that leukoreduction technology is an effective means to reduce the risk of three complications of transfusion: hla alloimmunization, cytomegalovirus transmission, and recurrent febrile nonhemolytic transfusion reactions. | |||||||
| 14692964 | HLA (HLA) | febrile nonhemolytic transfusion reactions | NA | NA | NA | negative | |
| proven clinical benefits of leukoreduced blood components include reduced febrile nonhemolytic transfusion reactions, alloimmunization against hla antigens, and cmv transmission. | |||||||
| 15248166 | HLA (HLA) | febrile nonhemolytic transfusion reactions | NA | NA | NA | unclassified | |
| leukoreduction of cellular blood products by filtration has been shown to decrease the incidence of febrile nonhemolytic transfusion reactions, transmission of leukocyte-associated viruses, and hla alloimmunization. | |||||||
| 20376259 | HLA (HLA) | febrile nonhemolytic transfusion reactions | NA | NA | NA | unclassified | |
| removal of leucocytes from various blood products has been shown to minimize febrile nonhemolytic transfusion reactions, hla alloimmunization, platelet refractoriness in multitransfused patients and prevention of transmission of leukotropic viruses such as ebv and cmv. | |||||||
| 9094979 | HLA-DR (HLA-DR) | cervical intraepithelial neoplasia | NA | NA | NA | positive+negation | |
| although there was also an up-regulation of hla-dr expression by cervical keratinocytes in cervical intraepithelial neoplasia lesions, as determined by immunohistochemistry, no significant correlation was found between hla-dr and cathepsin e expression in these lesions; neither was expression of cathepsin e correlated to the presence of hpv16, detected by polymerase chain reaction. | |||||||
Copyright 2024