PMID | Allele | Disease | Population | Drug Names | SNP | Class | Sentence |
---|---|---|---|---|---|---|---|
23454623 | HLA (HLA) | antiphospholipid syndrome | NA | aspirin | NA | positive | |
similar hla changes have been linked to autoimmune disorders, particularly antiphospholipid syndrome (aps), in which autoantibodies to phospholipid/protein complexes can trigger platelet activation. | |||||||
23454623 | HLA (HLA) | thrombophilia | NA | aspirin | NA | unclassified | |
aspirin insensitive thrombophilia: transcript profiling of blood identifies platelet abnormalities and hla restriction. | |||||||
31052398 | HLA-G (HLA-G) | antiphospholipid syndrome | Polish | NA | NA | unclassified | |
the hla-g 10101 allele seems to protect against antiphospholipid syndrome, which may be associated with increased serum shla-g levels in its carriers. | |||||||
32583563 | HLA-DR (HLA-DR) | antiphospholipid syndrome | NA | NA | NA | unclassified | |
the b 2 -glycoprotein i/hla-dr complex as a major autoantibody target in obstetric antiphospholipid syndrome. | |||||||
7773210 | HLA IDENTICAL (HLA-IDENTICAL) | chronic myeloid leukemias | NA | cyclophosphamide | NA | positive | |
we now report 38 patients (25 acute leukemias, 10 chronic myeloid leukemias, two myeloma; 24 in first cr/cp and 14 in more advanced phases of their disease) undergoing unmanipulated hla-identical sibling bmt following conditioning with cyclophosphamide and total body irradiation (tbi). | |||||||
7777271 | HLA-DR (HLA-DR) | vernal keratoconjunctivitis | NA | NA | NA | positive | |
vernal keratoconjunctivitis specimens as a whole showed higher counts than control specimens for cd3+, cd4+, hla-dr+, cd38+, eg2+, cd68+, ige+, fc epsilon ri+, iga+, igg+, and igm+ cells in the substantia propria; and for cd1a+, ige+, and eg2+ cells in the epithelium. | |||||||
8828547 | HLA-DR (HLA-DR) | vernal keratoconjunctivitis | NA | NA | NA | positive | |
we found significantly increased numbers of cd4+, cd45ro+, and hla-dr+ t cells in the conjunctiva of patients with atopic and vernal keratoconjunctivitis and giant papillary conjunctivitis, with a corresponding upregulation of markers present on antigen presenting cells. | |||||||
7782051 | HLA (HLA) | disease metabolic | NA | insulin | NA | negation | |
no correlation was found between serum tnf-alpha and chronologic age, duration of disease, metabolic control, insulin requirement and hla typing. | |||||||
10373080 | HLA MATCHED (HLA-MATCHED) | cyclophosphamide | NA | methotrexate | NA | unclassified | |
NA | |||||||
15497526 | HLA IDENTICAL (HLA-IDENTICAL) | acyclovir | NA | tacrolimus | NA | unclassified | |
NA |
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