Copyright 2024
| PMID | Allele | Disease | Population | Drug Names | SNP | Class | Sentence |
|---|---|---|---|---|---|---|---|
| 17142764 | HLA-A*01 | stem cell transplantation | NA | arginine | NA | unclassified | |
| this is the first example of the generation of cytotoxic t cells in the absence of proliferation of cd4(+) t cells (mixed lymphocyte culture) and the description of an aberrant allele, a*0118n, that may behave as a minor histocompatibility ag, with implications in allorecognition by cytolytic t cells in solid organ and stem cell transplantation. | |||||||
| 17183671 | HLA MATCHED (HLA-MATCHED) | stem cell transplantation | NA | NA | NA | positive | |
| minor histocompatibility (h) antigen mismatches significantly influence the outcome of hla-matched allogeneic stem cell transplantation. | |||||||
| 17302599 | HLA IDENTICAL (HLA-IDENTICAL) | stem cell transplantation | NA | NA | NA | unclassified | |
| allogeneic stem cell transplantation (sct) is best performed with an hla-identical sibling donor (matched related donor, mrd) to reduce the risk of early complications such as acute graft-vs.-host disease (agvhd). | |||||||
| 17384200 | HLA IDENTICAL (HLA-IDENTICAL) | stem cell transplantation | NA | NA | NA | unclassified | |
| ctla-4 polymorphisms and clinical outcome after allogeneic stem cell transplantation from hla-identical sibling donors. | |||||||
| 17389017 | HLA-C (HLA-C) | stem cell transplantation | NA | NA | NA | unclassified | |
| interaction of donor natural killer (nk)-cell-associated killer cell immunoglobulin-like receptors (kirs) with the patient's human leukocyte antigen-c (hla-c) ligands can result in an alloreactive nk response after haematopoietic stem cell transplantation. | |||||||
| 17412886 | HLA IDENTICAL (HLA-IDENTICAL) | stem cell transplantation | NA | NA | NA | only_studied | |
| to investigate whether eradication of cml after allogeneic stem cell transplantation (sct) was influenced by pr3 and ela2 gene expression or pr1-specific ctl responses, we studied cells from 87 cml patients and 27 hla-a*0201(+) donors collected prior to t-cell-depleted hla-identical sibling sct. | |||||||
| 17412886 | HLA-A*02 | stem cell transplantation | NA | NA | NA | only_studied | |
| to investigate whether eradication of cml after allogeneic stem cell transplantation (sct) was influenced by pr3 and ela2 gene expression or pr1-specific ctl responses, we studied cells from 87 cml patients and 27 hla-a*0201(+) donors collected prior to t-cell-depleted hla-identical sibling sct. | |||||||
| 17442774 | HLA IDENTICAL (HLA-IDENTICAL) | stem cell transplantation | NA | NA | NA | negation | |
| for those patients who do not have an hla-identical-related or -unrelated stem cell donor, a related three-loci mismatch haploidentical stem cell transplantation with t cell-depleted stem cells is a viable option. | |||||||
| 17452902 | HUMAN LEUKOCYTE ANTIGEN (HUMAN LEUKOCYTE ANTIGEN) | stem cell transplantation | NA | NA | NA | negative | |
| to determine the clinical significance of treg-content in stem cell grafts, we analyzed 58 human leukocyte antigen (hla)-identical sibling donors (34 patients received myeloablative and 24 patients reduced intense conditioning regimens) and correlated the treg frequency with clinical outcome after stem cell transplantation (sct). | |||||||
| 17550855 | HLA MISMATCHED (HLA-MISMATCHED) | stem cell transplantation | NA | NA | NA | unclassified | |
| and san hla-mismatched donor and a t-cell-depleted graft are known risk factors for epstein-barr virus (ebv) reactivation after stem cell transplantation. | |||||||
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