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| PMID | Allele | Disease | Population | Drug Names | SNP | Class | Sentence |
|---|---|---|---|---|---|---|---|
| 26068923 | HLA-CLASS I (HLA CLASS II) | viremia | Caucasian | NA | rs9264942 | unclassified | |
| aim of the studyassociation of two hla class i variants with hiv-1 pretreatment viremia, cd4+ t cell count at the care-entry and cd4+ t cell nadir. | |||||||
| 26068923 | HLA-B*57 | viremia | Caucasian | NA | rs9264942 | positive | |
| among cases with hla-b*5701 allele, significantly lower pretreatment viremia and higher baseline cd4+ t cell count were found (mean: 4.08 [sd: 1.2] vs. mean: 4.84 [sd:0.97] log hiv-rna copies/ml, p=0.003 and 431 vs. 270 cells/ml, p=0.04, respectively) compared to hla-b*5701 negative individuals. | |||||||
| 26068923 | HLA-B*57 | viremia | Caucasian | NA | rs9264942 | positive | |
| the lowest viremia (mean: 3.85 log [sd:1.3]) hiv-rna copies/ml and the highest baseline and nadir cd4+ t cell [median: 476 (iqr:304-682) vs. median: 361 (iqr: 205-574) cells/ml, respectively) were found in individuals with hla-b*5701(+)/hla-c -35 c/c haplotype. | |||||||
| 26068923 | HLA-C (HLA-C) | viremia | Caucasian | NA | rs9264942 | positive | |
| the lowest viremia (mean: 3.85 log [sd:1.3]) hiv-rna copies/ml and the highest baseline and nadir cd4+ t cell [median: 476 (iqr:304-682) vs. median: 361 (iqr: 205-574) cells/ml, respectively) were found in individuals with hla-b*5701(+)/hla-c -35 c/c haplotype. | |||||||
| 26169178 | HLA-DR (HLA-DR) | viremia | NA | NA | NA | positive+negation | |
| hla-dr(+)cd38(+)cd8(+) t cell levels in jrcsfnefdd infected mice did not rise above 1-2% despite sustained high levels of viremia. | |||||||
| 26663765 | HLA (HLA) | viremia | NA | NA | NA | negation | |
| single hla mismatches were not associated with viremia, suggesting that failing immune control likely involves multiple factors including maintenance immunosuppression. | |||||||
| 26684819 | HLA (HLA) | raltegravir | NA | maraviroc | NA | lack_of_evidence | |
| NA | |||||||
| 27194762 | HLA-CLASS I (HLA CLASS II) | viremia | South African | NA | NA | positive | |
| these results suggest that broad, highly functional cytotoxic t cells (cytotoxic t lymphocytes [ctls]) against the hiv-1 gag protein are associated with control among those with protective hla class i alleles and that loss of these responses eventually leads to viremia. | |||||||
| 28837858 | HLA (HLA) | viremia | NA | acyclovir | NA | unclassified | |
| the risk factors for hsv-1/2 viremia included hla disparity >=2 loci (p=0.049) and cytomegalovirus (cmv) reactivation (p=0.028). | |||||||
| 28921709 | HUMAN LEUKOCYTE ANTIGEN (HUMAN LEUKOCYTE ANTIGEN) | viremia | NA | NA | NA | unclassified | |
| donor race, donor age, human leukocyte antigen mismatches, serum creatinine, urinary protein, acute cellular rejection, acute antibody-mediated rejection, bk viremia, and cmv viremia were associated with allograft failure. | |||||||
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