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PMID Allele Disease Population Drug Names SNP Class Sentence
3457897 HLA-DRB1*04 motor neuron disease NA NA NA negative
forty six motor neuron disease patients from the newcastle upon tyne area had a reduced frequency of hla dr4 compared to the local control population.
3461931 HLA-DR2 (BROAD ANTIGEN) wolfram syndrome NA NA NA unclassified
two of three patients with wolfram syndrome had the hla-dr2 antigen.
3461931 HLA-DR2 (BROAD ANTIGEN) wolfram syndrome NA NA NA unclassified
the preponderance of the hla-dr2 antigen in the wolfram syndrome is different from classic type i diabetes.
21447263 HLA (HLA) wolfram syndrome NA insulin NA unclassified
[an evaluation of hla class 2 alleles and anti-islet antibodies as evidence for non-autoimmune diabetes in wolfram syndrome].
21447263 HLA (HLA) wolfram syndrome NA insulin NA unclassified
diabetes present in wolfram syndrome is a result of the selective b cell loss and failed insulin secretion which is probably associated with non-autoimmune pathogenesis.aim of the studythe aim of the study was an evaluation of hla subtypes and presence of b-cell autoantibodies in patients with molecularly confirmed wolfram syndrome.material and 9 patients with wolfram syndrome aged 10-24 years were examined.
21447263 HLA-DRB1*15 wolfram syndrome NA insulin NA positive
a comparison of the frequency of the hla alleles in patients with wolfram syndrome with type 1 diabetic children showed a more frequent presence of the drb11501 (p=0.03
21447263 NA (NA) wolfram syndrome NA insulin NA positive
a comparison of the frequency of the hla alleles in patients with wolfram syndrome with type 1 diabetic children showed a more frequent presence of the drb11501 (p=0.03
21447263 HLA-DQB1*01 wolfram syndrome NA insulin NA unclassified
polish patients with wolfram syndrome have a different profile of the hla antigens with the presence of dr2, dqw1 and drb3/4 allele and are negative for diabetes-related autoantibodies, which may confirm non-autoimmune b-cell destruction in this syndrome.
21447263 HLA-DR2 (BROAD ANTIGEN) wolfram syndrome NA insulin NA unclassified
polish patients with wolfram syndrome have a different profile of the hla antigens with the presence of dr2, dqw1 and drb3/4 allele and are negative for diabetes-related autoantibodies, which may confirm non-autoimmune b-cell destruction in this syndrome.
21447266 HLA (HLA) insulin NA glucose NA unclassified
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