Copyright 2024
| PMID | Allele | Disease | Population | Drug Names | SNP | Class | Sentence |
|---|---|---|---|---|---|---|---|
| 1992610 | HLA (HLA) | graft-versus-host disease | NA | cyclophosphamide | NA | unclassified | |
| neither the percentages nor the absolute numbers of host pbmc or gran were significantly affected by hla-matching, tbi dose-intensity, pretransplant remission status, subsequent development of acute or chronic graft-versus-host disease or relapse after transplantation. | |||||||
| 1992610 | HLA (HLA) | relapse | NA | cyclophosphamide | NA | unclassified | |
| neither the percentages nor the absolute numbers of host pbmc or gran were significantly affected by hla-matching, tbi dose-intensity, pretransplant remission status, subsequent development of acute or chronic graft-versus-host disease or relapse after transplantation. | |||||||
| 1994541 | HLA MATCHED (HLA-MATCHED) | transplantation | NA | NA | NA | unclassified | |
| marrow transplantation from hla-matched unrelated donors for treatment of hematologic malignancies. | |||||||
| 1994541 | HLA MATCHED (HLA-MATCHED) | hematologic malignancies | NA | NA | NA | unclassified | |
| marrow transplantation from hla-matched unrelated donors for treatment of hematologic malignancies. | |||||||
| 1994541 | HLA MATCHED (HLA-MATCHED) | transplantation | NA | NA | NA | unclassified | |
| less than 40% of the patients who could benefit from marrow transplantation have an hla-matched relative who can serve as a donor. | |||||||
| 1994541 | HLA-A (HLA-A) | transplantation | NA | NA | NA | unclassified | |
| this retrospective study analyzes the results of marrow transplantation for 52 patients receiving grafts from hla-a,b,dr,dw-phenotypically matched, mlc-compatible, unrelated volunteer donors compared to a disease, disease-stage, and age-matched cohort of 104 patients transplanted from hla-genotypically identical sibling donors. | |||||||
| 1994541 | HLA-DR (HLA-DR) | transplantation | NA | NA | NA | unclassified | |
| this retrospective study analyzes the results of marrow transplantation for 52 patients receiving grafts from hla-a,b,dr,dw-phenotypically matched, mlc-compatible, unrelated volunteer donors compared to a disease, disease-stage, and age-matched cohort of 104 patients transplanted from hla-genotypically identical sibling donors. | |||||||
| 1994541 | HLA MATCHED (HLA-MATCHED) | transplantation | NA | NA | NA | negation | |
| we conclude from this preliminary data that marrow transplantation from hla-matched unrelated donors should be considered in most, if not all, circumstances where transplantation from an hla-matched sibling would be indicated if such a donor were available. | |||||||
| 2001165 | HLA (HLA) | transplantation | NA | NA | NA | negation | |
| the question of whether or not hla is important in transplantation can now be answered with a definite yes. | |||||||
| 2001165 | HLA IDENTICAL (HLA-IDENTICAL) | cadaver | NA | NA | NA | unclassified | |
| one of the major factors influencing long-term survival is histocompatibility matching, as shown by the survival differences among hla-identical siblings (25-year half-life), one-haplotype-mismatched parental donors (12-year half-life), and two-haplotype-mismatched cadaveric donors (7-year half-life). | |||||||
Copyright 2024