PMID | Allele | Disease | Population | Drug Names | SNP | Class | Sentence |
---|---|---|---|---|---|---|---|
27976839 | HLA (HLA) | hematopoietic stem cell transplantation | NA | NA | NA | unclassified | |
the relevance of mismatching donor and recipient for hla variation outside the ard on hematopoietic stem cell transplantation (hsct) outcomes is unknown. | |||||||
28018351 | HLA-DPB1 (HLA-DPB1) | hematopoietic stem cell transplantation | NA | NA | NA | unclassified | |
allorecognition of hla-c mismatches by cd8+ t cells in hematopoietic stem cell transplantation is a complex interplay between mismatched peptide-binding region residues, hla-c expression, and hla-dpb1 disparities. | |||||||
28018351 | HLA-C (HLA-C) | hematopoietic stem cell transplantation | NA | NA | NA | unclassified | |
allorecognition of hla-c mismatches by cd8+ t cells in hematopoietic stem cell transplantation is a complex interplay between mismatched peptide-binding region residues, hla-c expression, and hla-dpb1 disparities. | |||||||
28018351 | HLA-C (HLA-C) | hematopoietic stem cell transplantation | NA | NA | NA | unclassified | |
hla-c locus mismatches (mms) are the most frequent class i disparities in unrelated hematopoietic stem cell transplantation (hsct) and have a detrimental impact on clinical outcome. | |||||||
28194615 | HUMAN LEUKOCYTE ANTIGEN (HUMAN LEUKOCYTE ANTIGEN) | hematopoietic stem cell transplantation | NA | adenosine | NA | unclassified | |
we review the various treatment approaches for ada scid including allogeneic hematopoietic stem cell transplantation (hsct) from a human leukocyte antigen-matched sibling or family member or from a matched unrelated donor or a haplo-identical donor, autologous hsct with gene correction of the hematopoietic stem cells (gene therapy-gt), and enzyme replacement therapy (ert) with polyethylene glycol-conjugated adenosine deaminase. | |||||||
28421078 | HUMAN LEUKOCYTE ANTIGEN (HUMAN LEUKOCYTE ANTIGEN) | hematopoietic stem cell transplantation | NA | NA | NA | unclassified | |
the outcome of hematopoietic stem cell transplantation (hsct) is controlled by genetic factors among which the leukocyte antigen human leukocyte antigen (hla) matching is most important. | |||||||
28558647 | HLA (HLA) | hematopoietic stem cell transplantation | NA | NA | NA | unclassified | |
knowledge of hla haplotypes is helpful in many settings as disease association studies, population genetics, or hematopoietic stem cell transplantation. | |||||||
28579987 | HLA-CLASS I (HLA CLASS II) | hematopoietic stem cell transplantation | NA | NA | NA | unclassified | |
the impact of natural killer (nk) cell alloreactivity on hematopoietic stem cell transplantation (hsct) outcome is still debated due to the complexity of graft parameters, hla class i environment, the nature of killer cell immunoglobulin-like receptor (kir)/kir ligand genetic combinations studied, and kir+ nk cell repertoire size. | |||||||
28629606 | HLA (HLA) | hematopoietic stem cell transplantation | NA | NA | NA | unclassified | |
regarding the crucial role of hla compatibility in transplantation and especially in hematopoietic stem cell transplantation, identification of hla polymorphisms at a high-resolution level is of major interest. | |||||||
28653354 | HUMAN LEUKOCYTE ANTIGEN (HUMAN LEUKOCYTE ANTIGEN) | hematopoietic stem cell transplantation | Latin American | NA | NA | unclassified | |
the total nucleated cell dosage of umbilical cord blood (ucb) is an important factor in determining successful allogeneic hematopoietic stem cell transplantation after a minimum human leukocyte antigen donor-recipient match. |
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